The United States Agency for International Development (USAID) is issuing a Request for Information (RFI) regarding the potential Western Cape Provincial Care and Treatment Activity aimed at improving HIV and TB epidemic control in South Africa. This initiative seeks input from both US and non-US organizations to gather insights that will inform the design of a program focused on enhancing local health systems and addressing the HIV/AIDS crisis comprehensively. The RFI emphasizes a collaborative approach to tackle significant public health challenges, aligning with South Africa’s National Strategic Plan and global UNAIDS objectives, particularly the "95-95-95" targets. Interested parties can submit their narrative and capability statements by April 29, 2024, and should direct inquiries to pretoriaapplications@usaid.gov or call +27 12 452 2000 for further information.