NINDS Sustainable Transformation of Institutional Research Rigor (STIRR) Program (RC2 - Clinical Trial Not Allowed)
ID: 356928Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356928

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-019.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced the Sustainable Transformation of Institutional Research Rigor (STIRR) Program, a federal grant opportunity aimed at enhancing research rigor and transparency within academic and research institutions in the field of neuroscience. This initiative seeks to support innovative programs and strategies that promote high-quality research practices, emphasizing rigorous study design and transparent reporting to foster a culture of scientific integrity. The NIH plans to allocate approximately $3.5 million annually for up to five awards, with individual grants ranging from $150,000 to $800,000 over a three-year period. Interested applicants must submit their proposals by October 17, 2025, and can find additional information and guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-NS-25-019-Full-Announcement.html
    RFA-NS-25-019.html
    The Department of Health and Human Services, through the National Institute of Neurological Disorders and Stroke (NINDS), has announced the Sustainable Transformation of Institutional Research Rigor (STIRR) funding opportunity. This initiative seeks to enhance research rigor and transparency in neuroscience by supporting programs that cultivate high-quality research within academic and research institutions. Emphasis is placed on innovative strategies promoting rigorous study design and unbiased reporting practices. Eligible applicants include various educational and nonprofit organizations, with funding estimated at $3.5 million annually for up to five awards. Each award may range from $150,000 to $800,000 over three years. The application process requires adherence to specific guidelines and the submission of distinct, non-duplicative proposals. Successful programs must demonstrate a commitment to improving local research practices, ensuring sustainability beyond the funding period, and sharing outcomes with the broader scientific community. This NOFO aims to catalyze a culture change respecting rigor and transparency in neuroscience research, fostering replicable practices across institutions involved in the NINDS mission.
    Similar Opportunities
    NINDS Sustainable Transformation of Institutional Research Rigor (STIRR) Program (RC2 - Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the NINDS Sustainable Transformation of Institutional Research Rigor (STIRR) Program, a federal grant opportunity aimed at enhancing research rigor and transparency within academic and research institutions in the field of neuroscience. This initiative seeks to implement innovative programs that promote rigorous study design and transparent reporting, ultimately fostering a culture of high-quality research practices. Grants ranging from $150,000 to $800,000 are available, with a total funding pool of $3.5 million anticipated for at least five awards annually. Applications are due by October 17, 2025, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries or visit the official announcement at https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-020.html for more details.
    STrengthening Research Opportunities for NIH Grants (STRONG): Structured Institutional Needs Assessment and Action Plan Development for Resource Limited Institutions (RLIs) (UC2 - Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the STrengthening Research Opportunities for NIH Grants (STRONG) program, which focuses on conducting structured institutional needs assessments and developing action plans for Resource Limited Institutions (RLIs). The initiative aims to enhance the research capacity of RLIs, which serve historically underrepresented populations in biomedical research and have received NIH support of $0 to $25 million annually over the past three fiscal years. This program is crucial for improving competitiveness for NIH funding and fostering research career development in diverse environments. Eligible institutions can apply for a maximum budget of $250,000 annually for a project period of three years, with applications due by September 18, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    Limited Competition: NIH Neuroscience Doctoral Readiness Program (DR. Program) (R25 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced the Limited Competition: NIH Neuroscience Doctoral Readiness Program (DR Program), aimed at enhancing the participation of individuals from diverse backgrounds in neuroscience research. This grant opportunity supports eligible domestic institutions in developing educational initiatives that include skills development and hands-on research experiences, specifically targeting postbaccalaureate participants from institutions with limited research opportunities. The program is critical for fostering a diverse biomedical research workforce and facilitating entry into rigorous doctoral programs in neuroscience, with funding anticipated to range from $1 million to $1.35 million for awards in FY 2026. Applications are due by March 26, 2025, and interested parties can contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Institutional Translational Research Training Program (T32 - Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the Institutional Translational Research Training Program (T32), a federal grant aimed at equipping advanced predoctoral students, postdoctoral fellows, and fellowship-stage clinicians with the skills necessary to advance basic research toward clinical application, particularly in the field of neuroscience. This program emphasizes a cohesive educational approach that integrates training in experimental design, statistical analysis, and effective communication, while fostering interdisciplinary collaboration among scientists and clinicians and providing exposure to industry and regulatory processes. The grant will cover stipends, tuition, and training-related expenses for a duration of two years, with a focus on enhancing diversity in biomedical research. Interested applicants can find more information and apply by May 25, 2026, and should direct inquiries to grantsinfo@nih.gov.
    NIH Neuroscience Development for Advancing the Careers of a Diverse Research Workforce (R25 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "NIH Neuroscience Development for Advancing the Careers of a Diverse Research Workforce (R25 Clinical Trial Not Allowed)" aimed at fostering a diverse research workforce in neuroscience. This initiative encourages applications from organizations proposing innovative mentoring and professional development activities to support individuals from underrepresented backgrounds in neuroscience research, focusing on enhancing retention and career advancement across various stages. The program is particularly significant for promoting diversity within the scientific workforce, which is essential for enhancing the quality and innovation potential of research. Interested applicants can apply for grants of up to $250,000 annually for a maximum of five years, with the application deadline set for September 26, 2025. For further inquiries, applicants may contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-23-178.html.
    Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the Innovation Grants to Nurture Initial Translational Efforts (IGNITE) funding opportunity, aimed at supporting pharmacodynamic, pharmacokinetic, and in vivo efficacy studies of therapeutic agents for neurological and neuromuscular disorders. This grant follows the R61/R33 phased award mechanism, where the R61 phase focuses on preparation and characterization, while the R33 phase emphasizes efficacy studies, with a critical transition contingent upon meeting specific milestones. The program encourages collaboration among various organizations, including nonprofit entities and academic institutions, to accelerate the development of promising therapies, with awards capped at $750,000 over a maximum project duration of three years. Interested applicants can find more information and application instructions at the NIH grants website, and the deadline for submissions is October 20, 2027.
    Limited Competition: Stimulating Access to Research in Residency Transition Scholar (StARRTS) (K38 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced the Limited Competition: Stimulating Access to Research in Residency Transition Scholar (StARRTS) grant opportunity, aimed at supporting clinician-investigators who have successfully completed the NIH StARR R38 program. This program provides 12-24 months of mentored research and career development support for individuals who have secured a clinical fellowship or early-career faculty appointment and propose a robust research and career development plan. The initiative is crucial for enhancing the transition of newly qualified clinician-researchers into independent research careers in biomedical fields, with a focus on advancing diversity within the clinician-scientist workforce. Interested applicants must submit their proposals by January 10, 2025, and can find additional information and application details at the NIH grants website or contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov.
    Imaging - Science Track Award for Research Transition (I/START) (R03- Basic Experimental Studies with Humans Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced the Imaging - Science Track Award for Research Transition (I/START) grant opportunity, aimed at supporting small research projects in the field of neuroimaging, particularly related to substance use and addiction. This funding initiative encourages both new and established investigators to conduct "proof of concept" studies that can generate pilot data within a short timeframe and with limited resources. Eligible applicants include a diverse range of organizations, such as historically black colleges and universities, tribal governments, and faith-based organizations, with funding of up to $150,000 available for projects lasting a maximum of one year. Interested parties should submit their applications by January 8, 2025, and can reach out to the NIH OER Webmaster at grantsinfo@nih.gov for further assistance.
    Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)." This initiative aims to support the characterization and efficacy studies of neurotherapeutic agents intended for treating neurological disorders, with a focus on conducting pharmacodynamic, pharmacokinetic, and in vivo efficacy studies to demonstrate the biological activity of proposed therapeutic agents. The program emphasizes the importance of rigorous experimental design, collaboration, and the inclusion of diverse perspectives in research teams, aligning with NIH's mission to translate research discoveries into effective therapies. Interested applicants can apply for funding up to $499,000 per year for a total project duration not exceeding three years, with the application deadline set for October 20, 2027. For further inquiries, applicants may contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-25-225.html.
    Imaging - Science Track Award for Research Transition (I/START) (R03- Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the Imaging - Science Track Award for Research Transition (I/START) funding opportunity, aimed at supporting small research grants (R03) in the field of neuroimaging, particularly related to substance use and substance use disorders. This initiative encourages both early-career and established researchers to adopt brain imaging methodologies for "proof of concept" studies, which are essential for generating preliminary data necessary for larger research applications. Grants of up to $150,000 are available for a one-year period, with a focus on inclusivity for underrepresented groups among eligible applicants, including various educational institutions and nonprofit organizations. Interested parties should submit their applications by January 8, 2025, and can reach out to the NIH OER Webmaster at grantsinfo@nih.gov for further assistance or inquiries regarding the application process.