Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Clinical Centers (U01 Clinical Trial Required)
Grant Opportunity Analysis
The National Institutes of Health invites applications from clinical centers to participate in a cooperative agreement consortium to test anti-obesity medication treatment strategies for children and adolescents. Awarded centers will conduct therapeutic clinical trials to optimize medication initiation timing, dosage, duration, and adjunct lifestyle therapies while maximizing benefits, minimizing risks, and promoting healthy developmental and mental well-being. Selected investigators must collaborate on protocol development, utilize common measures and standardized procedures for data and biospecimen collection, and analyze predictors of treatment response. The National Institute of Diabetes and Digestive and Kidney Diseases intends to commit $3,000,000 in direct costs to fund up to three awards, with a maximum budget of $1,000,000 in direct costs per year for a project period of up to five years. Applications must be submitted by October 9, 2026, and inquiries can be directed to Voula Osganian at voula.osganian@nih.gov.
Eligible Applicants
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.