The National Institutes of Health (NIH) is seeking a qualified entity to continue the Physiology of the Weight Reduced State (POWERS) Study through a cooperative agreement. This initiative aims to further investigate the physiological processes that contribute to individual differences in weight regain after weight loss, allowing for the completion of the clinical trial and subsequent data analysis. The POWERS study is critical for understanding obesity and developing effective weight management strategies. Interested applicants should note that the estimated project start date is April 1, 2027, with a single award anticipated, and they can contact Dr. Mary Evans at NIDDK_Obesity@nih.gov or by phone at 301-594-4578 for further information.