Cooperative AgreementPostedDiscretionary

Establishing Pediatric CNS Pharmacodynamic Measures as Tools to Enable Psychiatric Indications in Adolescents

National Institutes of Health
PAR-26-049
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Grant Opportunity Analysis

The National Institutes of Health (NIH) is offering a cooperative agreement opportunity titled "Establishing Pediatric CNS Pharmacodynamic Measures as Tools to Enable Psychiatric Indications in Adolescents." This initiative aims to advance research in determining optimal dosing strategies for new psychiatric medications in children and adolescents suffering from serious mental illnesses, focusing on the development of central nervous system (CNS) tools and models to assess medication effects on the brain. The opportunity is particularly relevant for researchers with expertise in pediatric psychiatry, neuroimaging, and clinical pharmacology, as it seeks to improve the safety and effectiveness of pediatric clinical trials through the establishment of pharmacodynamic measures. Interested applicants can reach out to Dr. Margaret C. Grabb at mgrabb@mail.nih.gov or by phone at 301-443-3563 for further information, with the estimated synopsis post date set for December 13, 2025, and the close date anticipated for February 13, 2026.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

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Project Timeline

postedOriginal Opportunity PostedSep 12, 2025

Funding Details

No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Cooperative Agreement

Grantor Contact

Name
Margaret C. Grabb, Ph.D.

CFDA Numbers

93.242

Official Sources