The U.S. Department of Labor’s Bureau of International Labor Affairs (ILAB) is issuing a Request for Information (RFI) aimed at gathering insights to enhance programming focusing on the intersection of disability rights and decent work. This initiative seeks to prevent discrimination, promote economic inclusion, and uphold disability rights in labor contexts, with a particular emphasis on strategies that empower individuals with disabilities. Responses to this RFI are voluntary and will inform potential future funding opportunities, but participation does not guarantee any advantages in subsequent procurement actions. The backdrop of this RFI highlights the broader frameworks guiding these efforts, including the Convention on the Rights of Persons with Disabilities and the Americans with Disabilities Act. The document provides a detailed overview of existing inequalities faced by persons with disabilities, emphasizing challenges in accessing education, employment, and necessary social protections. ILAB calls on stakeholders to share evidence regarding labor exploitation linked to disabilities and suggest effective national policies and practices that enhance educational and employment access. The aim is to develop a structured response to improve labor rights and reduce barriers faced by disabled individuals, while fostering inclusive practices across sectors. Responses are required by July 10, 2023, to designated email addresses.