Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)
ID: 343184Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $300K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/343184

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-23-056.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity through the Chemical Countermeasures Research Program (CCRP) Initiative, aimed at supporting basic research on the deleterious effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, such as fentanyl and carfentanil. This initiative seeks to identify and validate mechanisms, signaling pathways, and therapeutic targets to understand and mitigate the effects of UPS opioid overdose and its associated toxicities, including potential long-term health consequences. The program emphasizes interdisciplinary studies focusing on biological and molecular pathways involved in opioid toxicity, with a total funding amount of $2.5 million available for up to six awards. Interested applicants must submit their proposals by November 19, 2024, and can find additional information and submission guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DA-23-056-Full-Announcement.html
    RFA-DA-23-056.html
    The Chemical Countermeasures Research Program (CCRP) Initiative by the National Institutes of Health (NIH) aims to address public health risks associated with Ultra-Potent Synthetic (UPS) opioids, such as fentanyl and carfentanil, which pose both toxic and addictive threats. The funding opportunity supports research to identify mechanisms and therapeutic targets for mitigating the effects of acute UPS opioid exposure, including potential long-term health consequences. This initiative, through the R01 Research Project Grant mechanism, encourages interdisciplinary studies focusing on the biological and molecular pathways involved in opioid toxicity. Applications are due by November 17, 2024, with funding available for up to six awards totaling $2.5M in 2023. Eligible applicants include higher education institutions, nonprofits, and various government entities, while non-responsive applications will be discarded without review. The document details specific research objectives, eligibility criteria, submission guidelines, and evaluation processes, emphasizing the need for rigorous mechanistic studies to inform effective countermeasures against UPS opioid exposure.
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