Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations II (U24 Clinical Trial Not Allowed)
ID: 355318Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), has announced a Notice of Funding Opportunity (NOFO) titled "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations II," aimed at establishing a Coordinating Center (CC) to enhance collaborative psychiatric genetic studies focusing on underrepresented populations of non-European ancestry. The initiative seeks to address significant gaps in neuropsychiatric genetic research by facilitating data harmonization, coordinating training, and establishing ethical best practices within the Ancestral Populations Network (APN-2), ultimately promoting mental health equity. Eligible applicants include higher education institutions and nonprofit organizations, with awards structured as cooperative agreements reflecting substantial NIH involvement, and a maximum project period of five years. Interested parties should note that the application submission window opens on September 11, 2024, and closes on October 11, 2024; for further inquiries, contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    Files
    Title
    Posted
    The National Institutes of Health (NIH), specifically through the National Institute of Mental Health (NIMH), has released a Notice of Funding Opportunity (NOFO) titled "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations." This funding initiative seeks applications for a Coordinating Center (CC) to enhance collaborative efforts among large-scale psychiatric genetic studies focusing on populations of non-European ancestry, which are currently underrepresented in genomic research. The CC will facilitate data harmonization, coordinate training, and establish ethical best practices within the Ancestral Populations Network (APN-2). Key dates include a submission window opening on September 11, 2024, and applications closing on October 12, 2024. The coordinating center aims to address significant gaps in neuropsychiatric genetic research, ultimately advancing the goal of mental health equity. Eligible applicants include higher education institutions and nonprofit organizations. Awards will be cooperative agreements, reflecting substantial involvement from NIH staff, and the maximum project period is five years. The initiative emphasizes the importance of diverse representation in genomic research to uncover the genetic architecture of mental disorders effectively and improve global mental health outcomes.
    Similar Opportunities
    Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations II (U01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Genetic Architecture of Mental Disorders in Ancestrally Diverse Populations II (U01 Clinical Trial Not Allowed)" aimed at enhancing the understanding of psychiatric disorders in diverse populations, particularly those of African ancestry. This initiative seeks applications for cooperative agreements that will focus on accelerating gene discovery efforts and promoting global mental health equity, addressing the existing gap in genomic studies that predominantly center on European populations. The funding is intended to support innovative research approaches that incorporate community engagement and career development for underrepresented groups, with a project period of up to five years. Interested applicants can find more details and submit inquiries via the NIH Grants Information email at grantsinfo@nih.gov, with the application deadline set for February 13, 2026.
    Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH) (U01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH)" through a cooperative agreement aimed at advancing research in mental health. The initiative seeks to develop and optimize behavioral tasks that measure individual differences, enhancing clinical prediction and decision-making through the integration of behavioral measures and computational methods. This funding is crucial for fostering innovative clinical signatures that can improve the assessment and treatment of mental disorders, with a total funding amount of $15 million anticipated for FY 2025, allowing for up to six awards of $2.5 million each over a maximum project duration of five years. Interested applicants must submit their proposals by October 18, 2024, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Clinical Studies of Mental Illness (Collaborative R01) (Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Clinical Studies of Mental Illness (Collaborative R01)" aimed at supporting multidisciplinary clinical studies focused on mental health, particularly in areas such as genetics, biomarkers, and various mental illnesses. This initiative encourages collaboration across multiple sites to enhance sample sizes and diversity in participant recruitment, specifically targeting health disparity populations. The program allows for a project period of up to five years with no explicit budget limits, although proposed budgets must be well justified. Interested applicants, including various educational and nonprofit institutions, should submit their applications by January 7, 2026, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. For more details, applicants can refer to the full announcement available at https://grants.nih.gov/grants/guide/pa-files/PAR-23-050.html.
    Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), is offering a funding opportunity titled "Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)." This initiative invites interdisciplinary teams to apply for grants aimed at advancing the understanding of mental disorders through innovative neuroscience research, focusing on the underlying mechanisms of mental illnesses, the integration of basic and clinical neuroscience, and the neurobehavioral development of psychopathology. The program is designed to support collaborative projects that address complex scientific questions that cannot be pursued through standard research mechanisms, with funding available for up to five years and direct costs capped at $2 million annually. Interested applicants can find more information and application guidelines at the provided link, and they must submit their proposals by June 9, 2025.
    NIMH Mentoring Networks for Mental Health Research Education (R25 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a grant opportunity titled "NIMH Mentoring Networks for Mental Health Research Education (R25 Clinical Trial Not Allowed)" aimed at enhancing the training of the psychological and behavioral research workforce in the U.S. This program supports innovative educational activities focused on developing mentoring networks for graduate and medical students, postdoctoral scholars, and early-career investigators, with an emphasis on fostering professional growth and facilitating independent research trajectories in mental health. The initiative is crucial for expanding and diversifying the mental health research workforce, requiring applicants to detail their mentoring network's goals, structure, and participant recruitment methods, particularly from underrepresented groups. The grant has an award ceiling of $200,000, with applications due by May 25, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-23-263.html.
    Developmental AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), is inviting applications for Center Core Grants (P30) to establish Developmental AIDS Research Centers (D-ARC) focused on advancing research in mental health and HIV/AIDS. The program aims to support high-impact, interdisciplinary research across various domains, including NeuroHIV, behavioral science, and implementation science, while providing essential infrastructure to foster innovation and collaboration in HIV prevention and treatment strategies. Eligible applicants may request budgets up to $750,000 per year for a maximum of four years, with a strong encouragement for entities from underrepresented backgrounds to apply. The earliest application date is July 25, 2024, with final proposals due by 5 PM local time on August 25, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    Advancing Learning Health Care Research in Outpatient Mental Health Treatment Settings (R34 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Advancing Learning Health Care Research in Outpatient Mental Health Treatment Settings (R34 Clinical Trial Optional)," aimed at enhancing the implementation and sustainability of evidence-based practices in outpatient mental health and substance use treatment settings. This initiative encourages pilot studies that focus on data-driven learning health care, particularly in Certified Community Behavioral Health Clinics (CCBHCs), with objectives including addressing health disparities and improving crisis response services. Eligible applicants include a wide range of organizations, such as higher education institutions and community-based organizations, with funding available up to $450,000 over a three-year project period. The application submission period opens on May 16, 2024, and the final deadline for applications is January 8, 2026; for further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), is offering a funding opportunity for the Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required). This initiative aims to support pilot research focused on innovative psychosocial intervention strategies for both adults and children, emphasizing the experimental therapeutic approach to address underlying mechanisms of mental disorders. The funding will facilitate exploratory clinical trials for up to three years, with no specific budget limits, provided they reflect actual project needs, and applications must demonstrate a strong scientific rationale and empirical support. Interested applicants can find more information and application details at the provided NIH link, with a submission deadline of October 15, 2024.
    Population Genomic Screening in Primary Care Coordinating Center(U01 -Clinical Trials Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is soliciting applications for a Cooperative Agreement to establish a Coordinating Center focused on population genomic screening in primary care settings. This initiative aims to evaluate and implement screening for 4-7 common genomic conditions, emphasizing community engagement and the integration of healthcare equity, particularly for underserved populations. The program, managed by the National Human Genome Research Institute (NHGRI), seeks to develop frameworks for effective genomic screening practices while adhering to NIH’s data sharing and clinical trial registration policies. Interested applicants can access the full announcement at NIH Grants, with a funding commitment of $5.75 million over five years and an application deadline of December 2, 2024. For further inquiries, contact NIH Grants Information at grantsinfo@nih.gov.
    Confirmatory Efficacy Clinical Trials of Non-Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), is inviting applications for the Confirmatory Efficacy Clinical Trials of Non-Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required) grant. This funding opportunity aims to support clinical trials that assess the efficacy of non-pharmacological interventions for mental disorders in both adults and children, focusing on addressing unmet therapeutic needs and enhancing understanding of the mechanisms of action through rigorous experimental therapeutics approaches. The NIMH plans to commit approximately $27 million to fund various companion funding opportunities, with applications due by October 15, 2024. Interested applicants can find additional information and application procedures at the provided NIH link or contact the NIH OER Webmaster at FBOWebmaster@OD.NIH.GOV for assistance.