BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain
ID: 359068Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Small Businesses

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/359068
Timeline
    Description

    The National Institutes of Health (NIH) is announcing a funding opportunity titled "BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain," aimed at supporting research that develops computational tools for understanding dynamic brain circuits. This initiative encourages small businesses to create and disseminate theories, models, and methods that enhance the analysis of neural circuit mechanisms and functions, with a focus on collaborative investigations that integrate mechanistic and predictive models of neural dynamics. The estimated total program funding is $6 million, with applications expected to be solicited in the future; interested parties should prepare for submission by considering potential collaborations. For further inquiries, contact Jessica Mollick, PhD, at 301-827-2949 or via email at Jessica.mollick@nih.gov.

    Point(s) of Contact
    Jessica Mollick, PhD National Institute on Drug Abuse (NIDA), Division of Neuroscience and Behavior
    (301) 827-2949
    Jessica.mollick@nih.gov
    Files
    No associated files provided.
    Similar Opportunities
    BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity under the BRAIN Initiative, aimed at developing and validating novel tools to analyze cell-specific and circuit-specific processes in the brain. This initiative seeks proposals that focus on creating innovative technologies to enhance the understanding of complex neural behaviors and interactions, particularly tools that are non-invasive and applicable across various model organisms. The program is critical for advancing research in brain function and disorders, with an estimated funding total of $8 million to support 6-9 awards, and applications are due by May 7, 2024. Interested applicants must submit a Plan for Enhancing Diverse Perspectives (PEDP) and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for clinical studies aimed at advancing next-generation devices for recording and modulation in the human central nervous system, under the BRAIN Initiative. This initiative seeks to support small clinical trials that provide critical data necessary for the development of devices intended to treat central nervous system disorders, particularly those requiring an Investigational Device Exemption (IDE) from the FDA. The funding is crucial for enhancing neurotechnology and improving treatment outcomes, with NIH planning to allocate approximately $10 million annually for 5 to 7 awards, each with a maximum budget of $1.5 million per year for up to five years. Interested applicants can find more information and submit inquiries via grantsinfo@nih.gov, with applications due by September 28, 2026.
    BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative aimed at developing and validating novel tools to analyze cell-specific and circuit-specific processes in the brain. This initiative encourages interdisciplinary collaboration to enhance the understanding of complex neural circuits, focusing on the creation of innovative, high-precision techniques that can be applied across various species. Approximately $8 million will be allocated to support 6-9 awards, with applications due by February 9, 2027. Interested applicants must submit a Plan for Enhancing Diverse Perspectives and adhere to NIH policies throughout the application process; for further details, contact NIH Grants Information at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-170.html.
    BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System," aimed at advancing neuroscience research through innovative technology development. This initiative seeks applications for the creation of new hardware, software, or molecular constructs that address challenges in recording and modulating neural cells and circuits, with a focus on high-risk projects that could lead to transformative outcomes in understanding dynamic signaling within the central nervous system. The program allocates an estimated $10 million annually for 15-20 awards, emphasizing collaboration across scientific domains and encouraging participation from diverse institutions, particularly those supporting early-career researchers and underserved populations. Interested applicants should note that the application submission deadlines begin on May 2, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Basic Experimental Studies with Humans Required)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a grant opportunity titled "BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Basic Experimental Studies with Humans Required)." This initiative aims to solicit exploratory research projects that leverage invasive surgical procedures to record and stimulate neuronal activity in the human brain, focusing on understanding the dynamics of neuronal networks and their relation to human sensations, perceptions, and behaviors. The research is intended to lay the groundwork for future projects that utilize these invasive technologies, with successful applicants joining a consortium to establish standards of practice and share data within the scientific community. Interested small businesses can contact Dr. Merav Sabri at BRAINeROH@ninds.nih.gov or call 301-827-0908 for more information, with applications expected to be submitted by September 15, 2025, and project start dates anticipated for July 29, 2026.
    BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "BRAIN Initiative: Brain-Behavior Quantification and Synchronization – Transformative and Integrative Models of Behavior at the Organismal Level," aimed at advancing behavioral science through innovative research. This initiative seeks applications that focus on developing and validating tools for minimally invasive, high-resolution measurement of behavior, integrating multidimensional behavioral, neural, and environmental data, and creating new theoretical models to understand behavior as a complex dynamic system. With an anticipated funding commitment of approximately $8 million, the program emphasizes interdisciplinary collaboration and requires a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity. Interested applicants should submit their proposals by October 9, 2026, and can direct inquiries to grantsinfo@nih.gov for further information.
    BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a federal grant opportunity under the BRAIN Initiative for New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21). This initiative invites applications focused on developing innovative technologies to enhance the recording and manipulation of neural activity, particularly at unprecedented scales, while emphasizing the importance of diverse perspectives in the research process. The program aims to advance neuroscience research by addressing critical areas in understanding neural circuits and their functions, with an estimated total program funding of $200,000 and an award ceiling of $200,000 per project. Interested applicants must submit their proposals by June 15, 2026, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative, titled "New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)." This initiative aims to support proof-of-concept testing and the development of innovative neurotechnologies that can enhance the understanding of brain circuit dynamics and facilitate transformative neuroscience research. The program encourages high-risk, high-impact projects that integrate diverse scientific domains and require applicants to submit a Plan for Enhancing Diverse Perspectives (PEDP) as part of their proposals. The total estimated funding available is $10 million annually, with plans to support 15-20 awards over a maximum project period of three years. Interested applicants must adhere to strict submission guidelines, and the application deadline is January 20, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (U01 Clinical Trials Not Allowed)." This initiative aims to support research that develops and validates innovative tools for minimally invasive, high-resolution measurement of behavior in non-human animal models, while integrating multidimensional behavioral, neural, and environmental data to understand behavior as a complex dynamic system. The funding, which totals approximately $8 million for up to ten awards annually, emphasizes the importance of interdisciplinary collaboration and requires applicants to submit a Plan for Enhancing Diverse Perspectives (PEDP) as part of their proposals. Interested applicants should note that the application deadline is October 9, 2026, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative to support clinical studies aimed at advancing next-generation devices for recording and modulation within the human central nervous system (CNS). This initiative encourages proposals for early-stage clinical investigations, including first-in-human studies, that focus on treating CNS disorders and enhancing understanding of brain functions, particularly through Significant Risk studies requiring FDA Investigational Device Exemptions (IDEs) for chronic implants. The NIH plans to allocate approximately $10 million annually to fund 5 to 7 projects, emphasizing the importance of collaborations with device manufacturers through a public-private partnership program, and requires a Plan for Enhancing Diverse Perspectives as part of the application. Interested applicants can find more information and submit inquiries via grantsinfo@nih.gov, with the application deadline set for January 28, 2027.