Integrative Research to Understand the Impact of Sex Differences on the Molecular Determinants of AD Risk and Responsiveness to Treatment (U01 Clinical Trial Optional)
ID: 345317Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/345317

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-23-082.html
Timeline
    Description

    The National Institutes of Health (NIH) is inviting applications for a funding opportunity titled "Integrative Research to Understand the Impact of Sex Differences on the Molecular Determinants of AD Risk and Responsiveness to Treatment." This initiative aims to employ integrative experimental and analytical approaches to explore how sex differences influence Alzheimer's disease (AD) risk, brain aging, and treatment responsiveness, focusing on the interplay of genetic, environmental, and hormonal factors. The program encourages collaboration among experts in neuroscience, computational biology, and clinical research to address critical knowledge gaps in AD treatment and prevention strategies. Applications are due by February 21, 2025, with no cost-sharing requirements, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. More details can be found at the provided link: https://grants.nih.gov/grants/guide/pa-files/PAR-23-082.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-23-082-Full-Announcement.html
    PAR-23-082.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH) and the National Institute on Aging (NIA), has issued a Funding Opportunity Announcement (FOA) titled "Integrative Research to Understand the Impact of Sex Differences on the Molecular Determinants of AD Risk and Responsiveness to Treatment." This initiative calls for applications utilizing a cross-disciplinary approach to investigate how sex differences impact Alzheimer's disease (AD) risk, resilience, and treatment responsiveness. Key areas of interest include examining molecular changes during brain aging, understanding how sex interacts with genetic factors like ApoE, and the influence of hormonal states on AD risk. The initiative encourages collaboration between experts in neuroscience, computational biology, and clinical research. Applications must adhere to NIH guidelines, and emphasis is placed on rigorous data sharing and open science principles. Eligible applicants include a wide range of institutions and organizations, both US-based and foreign, with applications due by October 25, 2023, for new submissions and subsequent cycles until February 22, 2025. The FOA aims to fill critical knowledge gaps to improve treatment and prevention strategies for AD, underscoring a commitment to advancing health outcomes through targeted scientific inquiry.
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