Manufacturing: Monoclonal Antibody Reference Material
ID: NIST-MML-24-SS05Type: Sources Sought
Overview

Buyer

COMMERCE, DEPARTMENT OFNATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGYDEPT OF COMMERCE NISTGAITHERSBURG, MD, 20899, USA

Original Source

https://sam.gov/opp/d2758a1f8c574d01b77b966fcb89c4bd/view
Timeline
    Description

    Sources Sought COMMERCE, DEPARTMENT OF NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY is seeking vendors who can potentially perform additional upstream/downstream process development and scale-up to produce 1-5 kg of cNISTmAb from a single bioreactor run. The material is intended for research use and is not intended for animal or human consumption, clinical testing, or therapeutic use. The intent is to produce research-grade material in an environment representative of all salient features of biopharmaceutical biomanufacturing. Vendors should indicate their capabilities regarding "GMP-like" manufacturing, delivery of mAb at 100 mg/mL in L-Histidine, documentation/description of capabilities of biomanufacturing workflow, container closure for a 100 mg/mL mAb substance, assurance of homogeneity across individual mAb substance containers, batch records and/or process data, relevant experience handling CHOZN cell lines and manufacturing of biopharmaceutical products, and the ability to deliver a portion of the mAb as finished Reference Material. Interested parties should email a written response to donald.graham@nist.gov. NIST anticipates issuing a Request for Quotation in the second quarter and awarding a contract no later than the fourth quarter of fiscal year 2024.

    Point(s) of Contact
    Don Graham
    (301) 975-8567
    deg@NIST.GOV
    Files
    No associated files provided.
    Lifecycle
    Title
    Type
    Manufacturing: Monoclonal Antibody Reference Material
    Currently viewing
    Sources Sought
    Similar Opportunities
    Triple Quadrupole Mass Spectrometer with a Thermal Desorption-Based Ambient Ionization Source
    Buyer not available
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is seeking information from vendors regarding the procurement of a liquid chromatography triple quadrupole mass spectrometry system with a thermal desorption-based ambient ionization source. This system is intended to support the Surface and Trace Chemical Analysis Group's efforts in analytical chemistry and mass spectrometry, particularly for applications in forensic science, public health, and homeland security, as part of the Rapid Drug Analysis and Research (RaDAR) program. Interested parties are invited to submit their capabilities and relevant experience by emailing Donald Graham at deg@nist.gov, with responses due by the specified deadline, as NIST anticipates issuing a Request for Quotation in the third quarter and awarding a contract by the fourth quarter of FY2025. The small business size standard for this opportunity is 1,000 employees, and responses should adhere to the specified formatting guidelines.
    High Purity Material
    Buyer not available
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is conducting a sources sought notice to identify potential sources for high-purity materials to support the development of new reference materials for elemental composition. The procurement aims to acquire bulk solid materials with a purity of 99.999% or higher, specifically in the form of sputtering targets, which will be utilized in semiconductor manufacturing and other critical measurement applications. Interested vendors are encouraged to respond with their capabilities, including details on product specifications, customization options, and relevant services, by contacting Elizabeth Timberlake or Forest Crumpler via email. This notice serves as market research and does not constitute a commitment to issue a solicitation or award a contract.
    MIOX Vault AMB60SC Replacement Cell
    Buyer not available
    The National Institute of Standards and Technology (NIST) is seeking to procure a MIOX Vault AMB60SC Replacement Cell for its Gaithersburg, Maryland campus. The primary objective of this procurement is to replace a critical component of the on-site chemical generator that treats recirculated cooling tower water, ensuring effective control of harmful microorganisms. This replacement cell must meet specific performance criteria, including a generation capacity of 60 lb/day of free available chlorine and a water treatment capacity of 7.2 million gallons per day, with delivery expected within six weeks of order confirmation. The anticipated contract value is $42,300, and interested parties can reach out to Tony Schmidt at tony.schmidt@nist.gov for further inquiries.
    High-energy X-ray diffractometer with silver radiation
    Buyer not available
    The National Institute of Standards and Technology (NIST) is seeking information from vendors regarding the procurement of a high-energy X-ray diffractometer equipped with a silver radiation source. This instrument is essential for various NIST projects that require detailed understanding of local atomic order in materials and in situ studies of material processes, including AI-assisted synthesis of metal-organic frameworks and additive manufacturing of metals. The procurement aims to enhance capabilities in X-ray total scattering measurements, which are critical for advancing materials science research. Interested vendors should submit their capabilities and relevant information to Don Graham at deg@nist.gov by the specified response date, as NIST anticipates issuing a Request for Quotation in the third quarter of FY2025, with contract awards expected by the fourth quarter of FY2025.
    Mobile Manipulator System
    Buyer not available
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is conducting market research through a Sources Sought Notice for a Mobile Manipulator System. The objective is to identify potential sources capable of providing an advanced, integrated mobile manipulator that meets specific technical specifications for both indoor and outdoor applications, which will support NIST's development of performance metrics and standardized test methods for robotic systems. This procurement is crucial for enhancing NIST's capabilities in evaluating mobile manipulators, ensuring global competitiveness in robotics standards. Interested vendors should respond to Hunter Tjugum at hunter.tjugum@nist.gov by email, providing detailed information about their products and capabilities, with responses due within 7 business days of the notice issuance.
    Sources Sought Calcium PI Laser System
    Buyer not available
    The National Institute of Standards and Technology (NIST) is seeking information from vendors capable of providing a Calcium PI Laser System, which is crucial for their quantum computing and optical clock experiments involving trapped ions. The system must meet specific requirements, including two laser wavelengths (375 nm for photoionization and 422 nm for atomic excitation), continuous wave operation, high output power exceeding 30 mW, and minimal linewidth, along with advanced temperature and current electronics for remote operation. This procurement is vital for enhancing NIST's research capabilities in quantum measurement, emphasizing the need for precision and reliability in scientific experimentation. Interested parties should submit their capability statements to Lisa Stevens at lisa.stevens@nist.gov by the specified deadline, with no quotes being accepted at this time.
    High Pressure Chilled Mirror
    Buyer not available
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is conducting market research through a Sources Sought notice for a High Pressure Chilled Mirror hygrometer. The primary requirement is for a chilled-mirror hygrometer that can withstand pressures up to 7 MPa and has a reproducibility of 0.05 °C, aimed at enhancing measurement capabilities in industrial processes. This equipment is crucial for precise humidity measurement and control, which is vital in various scientific and industrial applications. Interested vendors must respond with detailed information about their products, including specifications and capabilities, by contacting Elizabeth Timberlake at elizabeth.timberlake@nist.gov, with responses encouraged before the closing date of May 21, 2025. This notice serves solely for market research and does not guarantee a contract award.
    Cylindrical Vacuum Chamber
    Buyer not available
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is seeking qualified contractors to provide a cylindrical vacuum chamber for high-precision measurements in its Physical Measurements Lab. This procurement, identified by Request for Quotations (RFQ) number 1333ND25QNB680190, requires the vacuum chamber to have a high vacuum capability of less than 7.5 × 10⁻⁷ Torr and must comply with specified technical requirements, emphasizing quality and adherence to industry standards. Interested contractors must submit electronic quotations by May 27, 2025, and ensure they are registered in the System for Award Management (SAM). For further inquiries, interested parties can contact Ranae M. Armstrong at ranae.armstrong@nist.gov or Donald Collie at donald.collie@nist.gov.
    Thyroid Bioassay Counter System
    Buyer not available
    The National Institute of Standards and Technology (NIST) is seeking responses for the procurement of a Thyroid Bioassay Counter System to enhance its radiation safety program at the Gaithersburg, Maryland campus. The system must be capable of monitoring personnel exposure to I-123, I-125, and I-131, featuring a mobile platform, advanced detection capabilities, and automated calibration functionalities. This procurement is critical for restoring NIST's ability to monitor radiation exposure effectively, ensuring compliance with safety regulations. Interested vendors should submit their responses, including company details and any feedback on the requirements, to Robert Singman at robert.singman@nist.gov by the specified deadline, as this notice is part of market research and does not constitute a commitment to award a contract.
    Cryogenic Microscope System
    Buyer not available
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is soliciting quotations for a Low-noise and low-drift closed-loop cryogenic microscope system to support its Quantum Measurement Division's research in quantum optics. The procurement requires vendors to deliver a system with specific technical features, including operational temperature capabilities and components for high-efficiency photon detection, with delivery expected within twenty weeks of order placement. This initiative is crucial for advancing quantum information science through the acquisition of technically advanced equipment for NIST laboratories. Interested vendors must ensure compliance with federal acquisition regulations and submit proposals based on the Lowest Price Technically Acceptable (LPTA) criteria, with inquiries directed to Ranae M. Armstrong at ranae.armstrong@nist.gov or Donald Collie at donald.collie@nist.gov.