RRPV Solicitation Summary: On-Demand Manufacturing
ID: RRPV-24-02-ODMType: Special Notice
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFOFFICE OF ASSISTANT SECRETARY FOR PREPAREDNESS AND RESPONSEBARDA - ASPR / DAAPPO / BARDA DCMAWASHINGTON, DC, 20515, USA

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714)

PSC

HEALTH R&D SERVICES; HEALTH CARE - OTHER; APPLIED RESEARCH (AN42)
Timeline
    Description

    The Department of Health and Human Services, specifically the Office of Assistant Secretary for Preparedness and Response (ASPR) through the Biomedical Advanced Research and Development Authority (BARDA), is seeking proposals for the "On-Demand Manufacturing" initiative under the Rapid Response Partnership Vehicle (RRPV) Consortium. The objective of this solicitation is to advance manufacturing technologies that enhance access and enable the rapid, cost-effective, and flexible production of vaccines and other biologics through decentralized manufacturing strategies. This initiative is crucial for improving the responsiveness of the healthcare system in times of need, particularly in the context of public health emergencies. Interested parties can find more information and access the full Request for Project Proposals (RPP) at the RRPV website, and inquiries can be directed to Rebecca Harmon at rebecca.harmon@ati.org.

    Point(s) of Contact
    Files
    No associated files provided.
    Lifecycle
    Title
    Type
    Similar Opportunities
    BARDA DRIVe EZ-BAA (EZBAA - 22-100-SOL-00003)
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the Biomedical Advanced Research and Development Authority (BARDA), is soliciting innovative research proposals under the Easy Broad Agency Announcement (EZ-BAA) BAA-22-100-SOL-00003, which is open until October 18, 2027. The initiative aims to address high-risk biomedical challenges related to public health emergencies, with specific Areas of Interest (AOIs) including drug repurposing, at-home diagnostics, and vaccine development. This program is crucial for enhancing the nation’s preparedness against emerging infectious diseases and other health threats, emphasizing the importance of innovative solutions in medical countermeasures. Interested parties must have active registration with SAM.gov and are encouraged to schedule pre-submission calls; key deadlines for abstract submissions vary by AOI, with multiple awards anticipated based on scientific merit and alignment with program goals.
    Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is soliciting innovative solutions aimed at enhancing the resilience of healthcare systems via its Resilient Systems Office (RSO). This opportunity invites submissions from eligible entities, including universities, nonprofits, and small businesses, to address systemic challenges in healthcare and public health by leveraging cutting-edge technologies that improve care quality and availability. The solicitation emphasizes the importance of sociotechnical system innovations and adaptive solutions that enhance the reliability and interoperability of health ecosystems. Interested parties must submit solution summaries for feedback before full proposal submissions, with the solicitation open until March 3, 2029. For further inquiries, submissions should be directed to the designated online platforms, and the primary contact email is provided in the solicitation details.
    Bulk Pharma Group B
    Health And Human Services, Department Of
    The Department of Health and Human Services (HHS) is seeking proposals for the procurement of a range of FDA-approved pharmaceuticals as part of the Bulk Pharma Group B initiative. The contract will require the delivery of specific injectable medications, including Acyclovir Sodium, Doxycycline, Levophed, Meropenem, Sodium Chloride, and sterile water, with quantities detailed in the attached Request for Proposal (RFP). This procurement is critical for maintaining the Strategic National Stockpile, ensuring a reliable supply of essential pharmaceuticals for disaster preparedness and response efforts. Interested vendors must submit their proposals by the specified deadline, and inquiries can be directed to primary contact Terri Reed at terri.reed@hhs.gov or secondary contact Kimberly Golden at kimberly.golden1@hhs.gov.
    BARDA DRIVe EZ-BAA-22-100-SOL-00003
    Health And Human Services, Department Of
    Solicitation: HEALTH AND HUMAN SERVICES, DEPARTMENT OF is seeking proposals for BARDA DRIVe EZ-BAA-22-100-SOL-00003. This procurement is for health research and development services, health care services, and experimental development. The announcement serves as a reissuance of the BARDA DRIVe EZ-BAA and supersedes prior iterations. For more information, please visit https://drive.hhs.gov/.
    DRAFT Innovative Solutions Opening ARPA-H PROactive Solutions for Prolonging Resilience (PROSPR)
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is soliciting proposals for the DRAFT Innovative Solutions Opening (ISO) under the PROactive Solutions for Prolonging Resilience (PROSPR) program. This initiative aims to extend the healthspan of Americans by developing interventions that address the underlying causes of age-related health decline, including establishing a predictive Intrinsic Capacity score and repurposing FDA-approved drugs. The program emphasizes a structured, multidisciplinary approach over a five-year timeline, focusing on key milestones such as in-home assessment technologies and decentralized clinical trials to enhance accessibility in health interventions. Interested proposers can find more information and submit inquiries via the PROSPR email box at PROSPR@arpa-h.gov, with a final ISO expected to be published at a later date.
    Office-Wide Innovative Solutions Opening for Scalable Solutions Office (SSO)
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is soliciting innovative solutions aimed at enhancing healthcare accessibility, affordability, and scalability. This opportunity invites universities, non-profits, small businesses, and similar entities to submit solution summaries and proposals that address health disparities, improve the distribution of healthcare technologies, and advance biomanufacturing innovations. The solicitation emphasizes the development of scalable technologies and collaborative distribution networks, with a focus on interdisciplinary approaches to revolutionize biomedicine and public health outcomes. Interested parties must submit their solution summaries by March 3, 2029, and can find further details and submission guidelines at https://solutions.arpa-h.gov. For inquiries, questions should be directed to the same website.
    Public Health Industrial Base Capabilities and Capacities: Anti-Microbials
    Health And Human Services, Department Of
    The Department of Health and Human Services (HHS) is seeking industry partners to provide information on domestic production capabilities related to anti-microbials as part of the Defense Production Act Title III Program. The objective is to gather data that will enhance the understanding of the Public Health Industrial Base (PHIB) and identify gaps in the marketplace that can be addressed through Title III authorities, which incentivize domestic production. This initiative is crucial for ensuring a reliable supply of essential health resources necessary for national defense and public health, particularly in light of the recent Presidential Determination 2024-03. Interested parties are invited to submit their responses by January 22, 2025, at 10 AM ET, to Chris Newell at IBMSC-Submissions@hhs.gov or Christopher.Newell@hhs.gov.
    Red Blood Cell Factory (RBC-Factory)
    Dept Of Defense
    The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals for the Red Blood Cell Factory (RBC-Factory) program, aimed at developing a medical device platform to enhance human red blood cells (RBCs) by inserting biologically active components. The primary objective is to create modified red blood cells (mRBCs) that can provide additional protections for warfighters operating in extreme environments, while also assessing the ethical, legal, and social implications (ELSI) of this technology. This initiative is critical for advancing military medical capabilities and ensuring the operational effectiveness of personnel in challenging conditions. DARPA has allocated approximately $18.1 million for this program, with proposals due by the specified deadlines, and interested parties can contact the BAA Coordinator at RBC-Factory@darpa.mil for further information.
    Office-Wide Innovative Solutions Opening for Health Science Futures (HSF)
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is soliciting proposals for the Innovative Solutions Opening (ISO) aimed at advancing healthcare technologies. This initiative seeks innovative, disease-agnostic research projects that can significantly improve health outcomes, focusing on areas such as maternal and fetal health, genetic therapies, and novel diagnostic tools. The solicitation emphasizes the development of transformative solutions rather than incremental research, with submissions required to follow a two-step process: an initial solution summary followed by a full proposal based on feedback received. Interested parties must submit their solution summaries by March 3, 2029, via the designated ARPA-H portal, and are encouraged to review the detailed submission guidelines outlined in the provided documentation.
    OUSD(R&E) Seeks Advanced Manufacturing, Prototypes and Materials (AMPAM)
    Dept Of Defense
    The Department of Defense, through the Office of the Undersecretary of Defense for Research and Engineering (OUSD(R&E)), is inviting companies to participate in the Advanced Manufacturing, Prototypes and Materials (AMPAM) initiative aimed at enhancing the defense industrial base. This opportunity encourages the submission of Concept White Papers and Quad Charts that propose innovative manufacturing processes and emerging technologies, with a focus on collaboration to develop and mature these capabilities for military applications. The initiative is critical for advancing national security objectives by integrating new manufacturing solutions, including advanced electronics, robotics, and additive manufacturing. Interested parties can submit proposals until the closing date of the Broad Other Transaction Announcement (BOTA), which remains open for three years, with periodic Capability Focus Areas (CFAs) issued for specific submissions. For inquiries, contact WHS RPAB at whs.mc-alex.ad.mbx.rpab@mail.mil.