The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is hosting a virtual Patients’ Day on February 25, 2025, to introduce the RAPID Program, which focuses on utilizing artificial intelligence (AI) and machine learning (ML) for precision diagnostics in rare diseases. The event aims to provide insights into the ARPA-H mission, program goals, and the involvement of Patient Experience (PX) Partners, encouraging participation from patient advocacy groups to enhance the development of innovative diagnostic support tools and comprehensive data integration. This initiative is crucial for addressing the diagnostic challenges faced by rare disease patients, particularly in democratizing access to diagnostics for underserved communities. Registration for the event opens on December 19, 2024, and closes on February 21, 2025; interested parties can reach out to the RAPID Email Box at RAPID@ARPA-H.gov for further information.