The Centers for Disease Control - CGH is seeking to develop, implement, and sustain high-quality comprehensive facility and community-based HIV 95-95-95 cascade activities for children, adolescents, and adults in Cameroon under the President's Emergency Plan for AIDS Relief (PEPFAR). This cooperative agreement aims to support strategies for improving HIV prevention, case identification, linkage, same-day ART initiation, ART adherence and retention, prevention of mother-to-child transmission (PMTCT), early infant diagnosis (EID), TB/HIV integration, viral load (VL) testing and suppression (VLS), HIV drug resistance testing, HIV surveillance, management of advanced HIV disease (AHD) and other HIV comorbidities including non-communicable diseases (NCDs), continuous use of patient-level data to inform clinical decision-making and improve patient outcomes, including the implementation of district-based programming to coordinate services delivery for health systems strengthening. The recipient(s) will be expected to implement innovative strategies to achieve and sustain the UNAIDS 95-95-95 goals across all subpopulations and provide technical assistance, capacity building, and differentiated models of case identification, care, and treatment across the HIV and HIV/TB clinical cascade including but not limited to infants, children, adolescents, men, pregnant and breastfeeding women (PBFW), and key and priority populations (KPs/PPs). The total funding amount for Year 1 is approximately $60,000,000, subject to the availability of funds. The application deadline is February 21, 2024, and electronically submitted applications must be submitted no later than 11:59 pm ET on the listed application due date. For more information, contact Emily Dale at pepfarfoas@cdc.gov.