The Division of Global HIV and Tuberculosis has issued a Notice of Funding Opportunity (NOFO) to enhance the capacity of civil society organizations (CSOs) in Uganda, aimed at accelerating HIV epidemic control by providing comprehensive prevention and treatment services to key populations under the PEPFAR initiative. The application deadline is February 18, 2025, with expected awards available starting September 30, 2025. The funding, totaling $10 million for the first year, will support 1-2 awards throughout a five-year period, focusing on key groups such as female sex workers, men who have sex with men, and adolescents. The NOFO aims to address legal and structural barriers, enhance service accessibility, and bolster collaboration between CSOs and health authorities. Eligible applicants include various organizations from local governments to non-profits, provided the project is conducted within Uganda. Proposals must adhere to rigorous guidelines, including a 20-page narrative limit and specific ME&R performance indicators. Successful applicants are expected to implement community-centered strategies that encompass data-driven approaches and sustainable service models, with a strong emphasis on reducing stigma and discrimination within healthcare settings. Overall, this funding opportunity seeks to support systemic improvements in HIV service delivery across Uganda.