The Department of Health and Human Services, through the National Institutes of Health (NIH), has issued a funding opportunity for research projects aimed at improving cancer screening and preventive services within populations experiencing health disparities. Under the R01 Research Project Grant, this initiative invites applications targeting barriers to cancer care, emphasizing collaborative efforts with community partners. Projects must develop interventions addressing issues at multiple levels, including patient, clinician, healthcare settings, and neighborhood/community factors. The funding seeks innovative approaches to enhance access and utilization of cancer preventive services, particularly for historically underserved groups identified by the NIH, such as racial minorities and sexual and gender minorities. The NoFO mandates a Plan for Enhancing Diverse Perspectives to promote inclusivity among researchers and participants. The application process outlines specific requirements, including adherence to application guidelines and timelines, funding limitations, and eligible institutions. The anticipated funding is contingent upon available resources and the merit of applications reviewed through a peer review process. This funding opportunity reflects the NIH's commitment to advancing health equity in cancer prevention and treatment.