The Health Resources and Services Administration (HRSA) is offering funding opportunities for two key initiatives: the Capacity Builder Provider (HRSA-25-055) and Evaluation Provider (HRSA-25-057) within its Street Medicine Interventions for People with HIV who are Unsheltered program. These initiatives aim to improve health outcomes for unsheltered individuals living with HIV through innovative street medicine interventions. The Capacity Builder will coordinate efforts to adapt and disseminate interventions, while the Evaluation Provider will conduct rigorous evaluations of the initiatives, utilizing implementation science frameworks to assess effectiveness and cost analysis across demonstration sites. Eligible applicants include public and private educational institutions, non-profits, and governments. Applications are due by March 11, 2025, with total funding available of $1,250,000 for the Capacity Builder and $1,000,000 for the Evaluation Provider. Both roles are expected to collaborate extensively to achieve the initiative's goals, which include enhancing access to care, providing technical assistance, and generating user-friendly materials for broader implementation. This effort aligns with the national objectives to better address the healthcare needs of marginalized populations and end the HIV epidemic in the U.S.