The U.S. National Science Foundation (NSF) is offering a federal grant opportunity titled "Cyberinfrastructure for Sustained Scientific Innovation" (CSSI), aimed at enhancing the capabilities of cyberinfrastructure to support scientific research and development. This program seeks proposals from eligible applicants, including non-profit organizations, institutions of higher education, and NSF-sponsored federally funded research and development centers, to create and deploy integrated cyberinfrastructure services that address evolving scientific needs. With an estimated total program funding of $34 million, the CSSI program anticipates three classes of awards: Elements, Framework Implementations, and Transition to Sustainability, each designed to foster collaboration and long-term impact in various scientific fields. Interested applicants should submit their proposals by December 1, 2025, and can reach out to NSF grants.gov support at grantsgovsupport@nsf.gov for assistance.