The Centers for Disease Control and Prevention (CDC) is forecasting a cooperative agreement opportunity aimed at localizing client-centered and quality service delivery support for a sustained HIV/TB response in the Kingdom of Eswatini, under the President's Emergency Plan for AIDS Relief (PEPFAR). The initiative seeks to enhance local capacity for delivering effective, evidence-based, and integrated HIV/TB prevention, care, and treatment services, while also building the technical and financial management capabilities of local health institutions. This funding is crucial for strengthening public health responses in Eswatini and is expected to total approximately $3,200,000 for the first fiscal year, with two awards anticipated. Interested applicants can reach out to Emily Dale at (404) 639-8880 or via email at pepfarfoas@cdc.gov for further details, with applications due by February 17, 2025, and awards expected to be announced by September 30, 2025.