The Centers for Disease Control and Prevention (CDC) is forecasting a cooperative agreement opportunity aimed at reducing the burden of parasitic infections in the United States through evidence-based prevention and control activities. The initiative focuses on three key components: enhancing healthcare provider knowledge and practices regarding Chagas disease, expanding public health surveillance and control activities for soil-transmitted helminths, and addressing other significant parasitic diseases of domestic concern. This funding is critical for improving public health outcomes and reaching at-risk populations, with an estimated total program funding of $10 million and an award ceiling of $1 million for up to seven awards. Interested applicants can contact Emily Dodd at 404-639-3753 or via email at iog2@cdc.gov, with applications due by May 2, 2025, and project start anticipated by September 30, 2025.