Single Source: The NIGMS Human Genetic Cell Repository (U42 - Clinical Trial Not Allowed)
ID: 351519Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Public and State Controlled Institutions of Higher Education

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/351519

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-055.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity through a cooperative agreement to support the NIGMS Human Genetic Cell Repository (HGCR), managed by the Coriell Institute for Medical Research. This initiative aims to maintain and expand a comprehensive collection of human cell lines and DNA samples, enhancing genetic services and providing these vital resources to qualified biomedical researchers. The repository currently holds over 11,900 cell lines and 5,900 DNA samples, with a maximum funding commitment of $1.75 million annually for up to five years, contingent upon a meritorious application. Interested applicants must adhere to NIH guidelines, with submission deadlines beginning May 10, 2024, and can direct inquiries to grantsinfo@nih.gov for further information.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-055-Full-Announcement.html
    PAR-24-055.html
    The National Institutes of Health (NIH) through the National Institute of General Medical Sciences (NIGMS) has announced a non-competitive funding opportunity to support a single award for the Coriell Institute for Medical Research to manage the NIGMS Human Genetic Cell Repository (HGCR). The initiative aims to maintain a comprehensive collection of human cell lines and DNA samples, acquire new specimens, and provide these resources to qualified biomedical researchers. The repository currently holds over 11,900 cell lines and 5,900 DNA samples. Key objectives include enhancing genetic services, expanding the database of cell lines, and implementing sustainability strategies for long-term operations. The project period will last up to five years, with a maximum funding commitment of $1.75 million annually, contingent upon a meritorious application. Eligibility is limited to the Coriell Institute, with specific requirements for diverse representation and inclusivity in research teams. Submission deadlines begin May 10, 2024, and applications must adhere strictly to NIH guidelines. Review criteria focus on the project's significance, investigator expertise, innovation, approach, and operational environment. The funding initiative underscores a commitment to advancing biomedical research by improving access to high-quality cellular resources.
    Similar Opportunities
    Research Resource for Human Organs and Tissues (U42 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Research Resource for Human Organs and Tissues" through a cooperative agreement mechanism (U42), aimed at supporting a program that provides and facilitates the availability of human tissues and organs for biomedical research. The initiative seeks to enhance the procurement, preservation, and distribution of diverse biospecimens, both normal and diseased, to aid researchers in understanding various diseases and addressing public health priorities. Applicants must demonstrate a proven track record in managing a human tissue and organ research resource, with direct costs capped at $720,000 over a potential five-year project period. The application period opens on December 24, 2024, with a submission deadline of September 25, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering funding through the opportunity titled "ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed)" to establish Expert Panels focused on the clinical relevance of genetic variants. The primary objective of this initiative is to develop a comprehensive knowledge base that enhances the interpretation of genes and genomic variants associated with high-priority diseases, utilizing established tools and resources from the Clinical Genomics Resource (ClinGen) and ClinVar. This funding is crucial for advancing genomic research and improving clinical outcomes through precision medicine, with a maximum award ceiling of $220,000 per year for a grant period of up to three years. Interested applicants must submit their proposals by May 25, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Genomic Community Resources (U24 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity (PAR-23-124) aimed at supporting the development of genomic community resources through cooperative agreements. This initiative seeks to enhance genomic research by funding projects that demonstrate broad applicability and significant value, focusing on the creation of genomic informatics tools, biological material collections, and community engagement efforts. The funded projects will play a crucial role in advancing both basic and clinical genomics research, with awards potentially lasting up to five years. Interested applicants, including a diverse range of organizations such as higher education institutions and nonprofits, must submit their applications by January 25, 2026, and can find further details and submission guidelines at NIH Grants. For inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for the Centers of Excellence in Genomic Science (CEGS) program, aimed at supporting innovative, interdisciplinary research in genomic science. This program seeks to establish academic centers that will develop transformative genomic approaches to address significant biomedical challenges, with a focus on integrating advanced technological and computational methods. Each award can provide up to $1.5 million per year for a maximum of five years, with potential renewal for an additional five years, and applications are due by June 23, 2025. Eligible applicants include a range of institutions such as higher education entities, nonprofits, and various government organizations, while foreign entities are not eligible. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    Human Brain Single-cell Genomics Explorer (U24 - Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Human Brain Single-cell Genomics Explorer" (U24 - Clinical Trial Not Allowed) to establish an integrated resource for analyzing and sharing de-identified human brain single-cell transcriptomics and epigenomics data. The initiative aims to develop a Single Cell Genomics Explorer that provides harmonized bioinformatics tools and a unified cell-type taxonomy, enhancing usability for researchers and ensuring datasets are Findable, Accessible, Interoperable, and Reusable (FAIR). With an estimated budget of $1 million and a project duration of three years, eligible applicants include a diverse range of organizations, such as Historically Black Colleges and Universities and Tribal Colleges, among others. Interested parties should note that applications are due by February 14, 2025, and can find further details at the provided NIH grants link or by contacting grantsinfo@nih.gov.
    NIDDK Central Repository Non-renewable Sample Access (X01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a grant opportunity titled "NIDDK Central Repository Non-renewable Sample Access," aimed at facilitating access to valuable biological samples for research in health-related fields, particularly diabetes, kidney, and digestive diseases. Eligible applicants, including various educational institutions and organizations, can apply for access to non-renewable samples and associated data from significant clinical studies, with the requirement to submit a report from the NIDDK Central Repository documenting sample availability. This initiative promotes equitable distribution of samples and collaboration among researchers to enhance research outcomes, with no funds awarded; instead, access approvals are based on the scientific merit of applications and sample availability. Interested parties should note that the application deadline is June 26, 2025, and are encouraged to engage with the Repository at least six weeks prior to submission for an assessment. For further inquiries, applicants can contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov.
    Notice of Intent to Publish a Funding Opportunity Announcement for Somatic Cell Genome Editing Translational Coordination and Dissemination Center (U24, Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is forecasting a funding opportunity for the establishment of a Somatic Cell Genome Editing Translational Coordination and Dissemination Center (TCDC) as part of its Somatic Cell Genome Editing (SCGE) program. The objective of this initiative is to accelerate the development of genome editing therapeutic agents by facilitating Investigational New Drug (IND) application enabling studies, establishing regulatory approval pathways, and disseminating successful strategies for initiating first-in-human clinical trials. This funding opportunity is crucial for advancing innovative therapeutic approaches in health, with an estimated total program funding of $2 million and the expectation of one award. Interested applicants can reach out to Dr. Marrah Lachowicz-Scroggins at SCGEprogram@od.nih.gov or by phone at 301-827-8229 for further details, with the anticipated application due dates in Summer 2022 and an estimated award date of April 1, 2023.
    Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for access to high-throughput sequencing and genotyping services through the Center for Inherited Disease Research (CIDR). This initiative aims to facilitate the identification of genetic factors contributing to human health and disease by providing NIH-supported investigators with specialized genomic services and statistical genetics support that are not feasible in individual laboratories. The CIDR's state-of-the-art technologies are crucial for advancing collaborative research efforts in genetic studies. Applications are accepted continuously, with a maximum project period of five years, although no direct funding is provided through this award. Eligible applicants include a wide range of institutions, including higher education institutions, nonprofits, and government organizations, with a focus on enhancing data-sharing projects. For further details, interested parties can contact NIH Grants Information at grantsinfo@nih.gov, and the application deadline is July 8, 2026.
    Advancing Genomic Medicine Research (R01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting proposals for the "Advancing Genomic Medicine Research (R01 Clinical Trial Optional)" grant, aimed at stimulating innovative research in the implementation of genomic technologies in clinical care. This funding opportunity emphasizes addressing health disparities and requires applicants to develop a Plan for Enhancing Diverse Perspectives to ensure inclusivity in research teams and participant recruitment. The initiative seeks to explore the value of genomic data in improving clinical outcomes, identify barriers to implementation, and develop effective data-sharing methods, with approximately $2.4 million available for three awards and an additional $700,000 for one award in fiscal year 2024. Applications are due by February 12, 2025, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Advancing Genomic Medicine Research (R03 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Advancing Genomic Medicine Research (R03 Clinical Trial Not Allowed)" aimed at stimulating innovation in the implementation and sharing of genomic information in clinical care across diverse populations. This initiative encourages applications for small research projects that explore the integration of genomic data into clinical practice, assess barriers to implementation, and develop innovative data analysis techniques, particularly focusing on underrepresented populations in genomic research. The maximum budget for each application is $50,000 over a two-year period, with a total funding expectation of approximately $150,000 for FY 2024. Interested applicants must submit their proposals by February 12, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.