The National Institutes of Health (NIH) through the National Institute of General Medical Sciences (NIGMS) has announced a non-competitive funding opportunity to support a single award for the Coriell Institute for Medical Research to manage the NIGMS Human Genetic Cell Repository (HGCR). The initiative aims to maintain a comprehensive collection of human cell lines and DNA samples, acquire new specimens, and provide these resources to qualified biomedical researchers. The repository currently holds over 11,900 cell lines and 5,900 DNA samples. Key objectives include enhancing genetic services, expanding the database of cell lines, and implementing sustainability strategies for long-term operations. The project period will last up to five years, with a maximum funding commitment of $1.75 million annually, contingent upon a meritorious application. Eligibility is limited to the Coriell Institute, with specific requirements for diverse representation and inclusivity in research teams. Submission deadlines begin May 10, 2024, and applications must adhere strictly to NIH guidelines. Review criteria focus on the project's significance, investigator expertise, innovation, approach, and operational environment. The funding initiative underscores a commitment to advancing biomedical research by improving access to high-quality cellular resources.