The Department of Health and Human Services is offering a funding opportunity titled "Enhancing Reuse of NHGRI Data Assets" under the R03 Small Grant Program, aimed at leveraging genomic datasets available through the National Human Genome Research Institute's (NHGRI) AnVIL platform. The initiative encourages innovative research and secondary analysis projects utilizing large data sets generated predominantly by NHGRI-funded initiatives. Approximately $1 million will be allocated annually for up to seven awards over two years with a budget limit of $125,000 in direct costs per project. Key dates include an application due date of January 14, 2025, with a maximum project period of two years, and all proposed research must utilize AnVIL workspaces. The application is non-competitive to clinical trials, emphasizing research that enhances genomic understanding and addresses biomedical questions. Eligible applicants include a range of institutions and organizations, including higher education institutions and various nonprofit entities. The program will require successful candidates to attend annual AnVIL community conferences, provide feedback on user experience, and comply with NIH data management policies. This opportunity reflects the government's commitment to advancing genomics research and establishing greater accessibility to genomic data for a wider research community.