The National Institutes of Health (NIH) is inviting research grant applications for the Behavioral and Integrative Treatment Development Program (R01 Clinical Trial Optional), aimed at advancing the development and testing of behavioral therapies for substance use disorders. This initiative encourages research that focuses on the efficacy of interventions, mechanisms of behavior change, and the optimization of treatment approaches, particularly for drug and alcohol dependence, through a structured three-stage research process. The program emphasizes the importance of innovative treatment strategies and community engagement to improve outcomes for diverse populations affected by addiction. Interested applicants can find more information and submit inquiries via the NIH OER Webmaster at OERWebmaster03@od.nih.gov, with the application deadline set for March 21, 2025.