The National Institutes of Health (NIH) is inviting applications for the Collaborative Opportunities for Multidisciplinary, Bold, and Innovative Neuroscience (COMBINE) program, which aims to support interdisciplinary research teams in addressing significant challenges in neuroscience. This funding opportunity is designed for integrated efforts involving three to six principal investigators (PIs) working collaboratively towards a singular, impactful goal over a defined five-year period, emphasizing innovative approaches and diverse scientific perspectives. The program anticipates committing up to $10 million annually to fund 4-6 projects, with individual budgets ranging from $500,000 to $1.5 million. Applications are due by October 9, 2024, and interested parties can find more information and guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.