DOD Amyotrophic Lateral Sclerosis, Therapeutic Development Award
ID: 353166Type: Posted
Overview

Buyer

Dept. of the Army -- USAMRAA (DOD-AMRAA)

Eligible Applicants

Unrestricted

Funding Category

Science and Technology and other Research and Development

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/353166
Timeline
    Description

    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY24 Amyotrophic Lateral Sclerosis (ALS) Therapeutic Development Award, aimed at advancing research from preclinical therapeutic validation to FDA Investigational New Drug (IND)-enabling studies. This grant supports empirical, product-driven studies with a focus on lead compounds and requires proof-of-concept efficacy data in at least one preclinical model system of ALS. With an estimated total program funding of $9.6 million and the expectation of awarding four grants, eligible applicants include unrestricted entities such as non-profit organizations, for-profit companies, and academic institutions, with direct costs capped at $1.5 million for projects lasting up to three years. Interested applicants must submit a pre-application followed by a full application via eBRAP or Grants.gov by the deadline of July 10, 2024, and can reach out to the CDMRP Help Desk at help@eBRAP.org for further assistance.

    Point(s) of Contact
    help@eBRAP.org
    Files
    Title
    Posted
    HT942524ALSRPTDA_GG2.pdf
    The Department of Defense (DOD) is announcing the FY24 Amyotrophic Lateral Sclerosis (ALS) Therapeutic Development Award, part of the Defense Health Program aimed to foster impactful research in ALS. This program invites applications for projects that can progress from preclinical therapeutic validation to FDA Investigational New Drug (IND)-enabling studies, with a total funding of approximately $40 million allocated for FY24. Eligible applicants include non-profit and for-profit organizations, as well as academic institutions, with direct costs not exceeding $1.5 million for a project duration of up to three years. The application process consists of a two-step submission: a pre-application followed by a full application, through either the eBRAP or Grants.gov platforms. Review criteria emphasize the significance of the therapeutic rationale, research strategy, feasibility, and potential clinical impact. Special attention is given to the use of biomarkers in therapeutic development. The federal funding's expected outcomes include advancing ALS treatments and improving patient care. This initiative highlights a commitment to accelerating ALS research and the importance of sound scientific collaboration.
    HT942524ALSRPTDA.pdf
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