The Centers for Disease Control and Prevention (CDC) is offering a federal grant opportunity aimed at identifying and evaluating potential risk factors for Amyotrophic Lateral Sclerosis (ALS). This initiative seeks investigator-initiated research proposals that focus on various factors, particularly those related to military service, contact sports, traumatic brain injury, neuroinflammation, and infectious agents, with three distinct funding options available to support different types of research. The total estimated program funding is $7.5 million, with individual awards ranging from $0 to $500,000, and the agency anticipates making approximately eight awards. Interested applicants must submit their proposals electronically by November 4, 2024, and can direct inquiries to Candis M. Hunter, PhD, at ncipc_erpo@cdc.gov.