Toxic Exposures Clinical Trial Award
ID: 355156Type: Posted
Overview

Buyer

Dept. of the Army -- USAMRAA (DOD-AMRAA)

Eligible Applicants

Unrestricted

Funding Category

Science and Technology and other Research and Development

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/355156
Timeline
    Description

    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Fiscal Year 2024 (FY24) Toxic Exposures Clinical Trial Award (CTA) to support clinical trials focused on military-related toxic exposures. This funding opportunity aims to facilitate research that addresses the prevention, diagnosis, treatment, and underlying mechanisms of health issues stemming from such exposures, with applicants required to align their proposals with at least one FY24 Toxic Exposures Research Program (TERP) Goal and Topic Area. The initiative is crucial for advancing understanding and management of health consequences related to military service, with a total funding pool of $30 million available, including direct costs capped at $1.5 million for single Principal Investigator (PI) projects and $2.5 million for partnering PI applications. Key deadlines include a pre-application due by August 13, 2024, and a full application by November 7, 2024; interested parties can reach out to the CDMRP Help Desk at help@eBRAP.org for further assistance.

    Point(s) of Contact
    help@eBRAP.org
    Files
    Title
    Posted
    HT942524TERPCTA-GG.pdf
    The Department of Defense (DOD) is offering the Fiscal Year 2024 (FY24) Toxic Exposures Clinical Trial Award (CTA) through the Toxic Exposures Research Program (TERP) to support research addressing military-related toxic exposures. This funding opportunity is aimed at clinical trials that will investigate prevention, diagnosis, treatment, and the underlying mechanisms of health issues caused by such exposures. Applicants must align their proposals with at least one FY24 TERP Program Goal and Topic Area, which include elucidating toxic exposure mechanisms and developing therapeutics. Key deadlines include a pre-application by August 13, 2024, and a full application by November 7, 2024. The total funding available is $30 million, with direct costs limited to $1.5 million for single PI projects and $2.5 million for partnering PI applications. Eligible applicants include both extramural and intramural organizations, and the application process involves a two-step submission through the Electronic Biomedical Research Application Portal (eBRAP) and Grants.gov. Proposals emphasizing collaborative efforts with the Department of Veterans Affairs and focusing on military health outcomes are encouraged. The initiative underscores a commitment to understanding and addressing health consequences related to military service exposures.
    Similar Opportunities
    DoD Toxic Exposures Translational Research Partnership Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Toxic Exposures Translational Research Partnership Award (TRPA) to support collaborative research addressing military-related toxic exposures. This grant aims to foster interdisciplinary partnerships among Principal Investigators (PIs) to advance translational research that integrates basic science with clinical applications, focusing on health care products, interventions, and clinical practice guidelines. Approximately $4.48 million is available for two awards, with each award capped at $2.24 million, and applications are due by October 16, 2025. Interested applicants can reach out to the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507 for further information.
    DoD Toxic Exposures Investigator-Initiated Research Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Toxic Exposures Investigator-Initiated Research Award (IIRA) to support research on military-related toxic exposures and their health impacts. This grant aims to fund studies across various research phases, including basic laboratory research, translational research, and preclinical studies, with a total estimated funding of approximately $3.85 million to support around five projects, each receiving a maximum of $770,000 over three years. The program is crucial for advancing understanding and treatment of health conditions associated with toxic exposures faced by service members and veterans. Interested applicants, including both domestic and foreign organizations, must submit pre-applications by July 29, 2025, with full applications due by October 16, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD Peer Reviewed Medical Research Program, Clinical Trial Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a grant opportunity under the Peer Reviewed Medical Research Program (PRMRP) for the fiscal year 2025, specifically for the Clinical Trial Award (CTA). This program aims to support the rapid implementation of clinical trials that can significantly impact the treatment or management of diseases relevant to military health, with a focus on areas such as autoimmune disorders, cardiovascular health, infectious diseases, and neuroscience. Approximately $32 million is available for this initiative, with an expected four awards, each capped at $8 million, and applications are due by July 21, 2025. Interested applicants can reach out to the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507 for further assistance.
    DOD Peer Reviewed Cancer, Clinical Trial Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a grant opportunity for the fiscal year 2025 under the Peer Reviewed Cancer Research Program (PRCRP) Clinical Trial Award (CTA). This grant aims to support the rapid implementation of clinical trials that have the potential to significantly impact cancer treatment, specifically targeting designated cancer types relevant to military health. The program emphasizes the importance of advancing cancer research to benefit service members, veterans, and their families, with funding available for projects ranging from initial proof-of-concept trials to large-scale phase III trials, capped at a total cost of $4.2 million over a maximum performance period of four years. Interested applicants must submit pre-applications by June 20, 2025, followed by full applications due by September 25, 2025, and can reach out to the CDMRP Help Desk at help@eBRAP.org for further assistance.
    DOD Peer Reviewed Cancer, Idea Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the fiscal year 2025 Peer Reviewed Cancer Research Program (PRCRP) Idea Award to support innovative cancer research that prioritizes military health. This grant aims to fund high-risk, high-reward proposals that focus on specific cancer types relevant to Service Members, Veterans, and their families, with an emphasis on introducing new paradigms in cancer care and addressing environmental exposure risks. With an estimated total program funding of approximately $14 million, the program anticipates awarding around 25 projects, each with a maximum funding limit of $560,000 for a duration of up to two years. Interested applicants must submit a pre-application by June 20, 2025, followed by a full application due by September 25, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD Peer Reviewed Medical Research Program, Technology/Therapeutic Development Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Peer Reviewed Medical Research Program (PRMRP) Technology/Therapeutic Development Award (TTDA) to support the translation of promising preclinical findings into clinical applications for military personnel, veterans, and their families. This grant aims to facilitate the development of products that address military-related health challenges, including prevention, detection, diagnosis, treatment, or quality of life improvements, with a focus on innovative approaches in areas such as autoimmune disorders and infectious diseases. With an estimated total program funding of approximately $41.25 million available for up to 11 awards, applicants must submit a two-step application process, including a pre-application and a full application, by the closing date of July 21, 2025. For further inquiries, interested parties can contact the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507.
    DOD Duchenne Muscular Dystrophy, Clinical/Translational Research Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a grant opportunity for the Duchenne Muscular Dystrophy Research Program's Clinical/Translational Research Award (CTRA) for fiscal year 2025. This funding initiative aims to support advanced translational research that accelerates promising ideas in Duchenne muscular dystrophy (DMD) into clinical applications, particularly focusing on therapies effective across all age groups, including infants and nonambulatory individuals. With an estimated total program funding of approximately $8.56 million, the program anticipates awarding around five grants, encouraging collaborations with early-career investigators and requiring applications to include preliminary data relevant to DMD. Interested applicants should note that a pre-application is due by July 25, 2025, with full applications due by August 8, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD Military Burn, Patient-Centered Research Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Military Burn Research Program's Patient-Centered Research Award (PCRA) to enhance clinical practices and interventions for burn victims in combat conditions. This grant opportunity, with an estimated total funding of $3.4 million, specifically supports clinical research involving human subjects, excluding preclinical studies, and aims to bridge the gap between research and practical application in austere environments. Proposals should focus on improving acute burn care practices, developing methods to prevent and treat cold injuries, and managing complications such as fluid resuscitation and inhalation injuries, with a strong emphasis on military health relevance and potential impact. Interested applicants must submit pre-applications by June 23, 2025, and full applications by September 8, 2025, with funding announcements expected by September 30, 2026. For further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD Peer Reviewed Cancer, Impact Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Peer Reviewed Cancer Research Program (PRCRP) Impact Award to support high-impact research aimed at improving clinical cancer care relevant to military health. This grant seeks mature research projects that demonstrate potential for near-term benefits in cancer treatment and patient outcomes, particularly focusing on specific cancer types such as bladder, blood, and brain cancers, while excluding melanoma and breast cancers. The program emphasizes the importance of preliminary data, collaboration with Department of Defense (DOD) and Veterans Affairs (VA) entities, and rigorous study designs to advance cancer detection and treatment for service members and their families. The estimated total program funding is $45.5 million, with individual awards capped at $1.4 million for single Principal Investigator applications and $1.75 million for partnering applications, over a maximum period of three years. Interested applicants must submit a pre-application by September 25, 2025, and can contact the CDMRP Help Desk at help@eBRAP.org for further assistance.
    DOD Amyotrophic Lateral Sclerosis, Pilot Clinical Trial Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Amyotrophic Lateral Sclerosis Research Program (ALSRP) Pilot Clinical Trial Award to support clinical trials aimed at improving the treatment and management of Amyotrophic Lateral Sclerosis (ALS). Applicants are required to focus on either biomarker-driven interventions or enhancements in clinical care, with an emphasis on incorporating community collaboration to optimize research impact. This funding opportunity allocates approximately $6.6 million to support around two pilot clinical trial applications, with a direct cost cap of $2 million for each project. Interested parties must submit a pre-application by June 6, 2025, followed by a full application due on August 27, 2025. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507.