The National Institutes of Health (NIH) has announced a funding opportunity for research on Alzheimer's Disease (AD) and its related dementias (ADRD) through the R21 grant mechanism. This initiative aims to support exploratory and developmental research that introduces innovative models, tests, and techniques to enhance understanding and treatment of AD/ADRD, with a focus on high-priority topics to be defined in future notices. The grant allows a diverse range of organizations, including universities, non-profits, and tribal governments, to apply for funding, with a budget cap of $275,000 for each two-year project and a maximum direct cost of $200,000 in any single year. Interested applicants should note that the application deadline is November 12, 2024, and can direct inquiries to the NIH OER Webmaster at OERWebmaster03@od.nih.gov for further information.