The Centers for Disease Control and Prevention (CDC) has announced a Notice of Funding Opportunity (NOFO) titled "Develop and Test HIV Prevention Interventions for Black and Hispanic Gay, Bisexual, and Other Men Who Have Sex with Men Who Use Substances." This initiative aims to support pilot research focused on developing and testing behavioral implementation strategies for biomedical interventions, such as oral PrEP and condom use, to enhance HIV and STI prevention among disproportionately affected populations, particularly Black and Hispanic men who have sex with men (MSM) who report substance use. The funding, totaling $2.85 million, is intended for a three-year performance period, with two awards expected, each ranging from $350,000 to $475,000. Interested applicants must submit their proposals by February 20, 2025, with the project anticipated to commence on September 1, 2025. For further inquiries, applicants can contact Jocelyn Patterson Mosley at JPatterson@cdc.gov.