The U.S. Department of Health and Human Services, through the Office of the National Coordinator for Health Information Technology, has released a Notice of Funding Opportunity (NOFO) for Leading Edge Acceleration Projects (LEAP) in Health Information Technology. This initiative aims to tackle significant challenges in the accessibility, exchange, and use of interoperable health IT systems. The funding opportunity focuses on two Areas of Interest: (1) improving health equity and social determinants of health via innovative technology tools and electronic health records, and (2) utilizing equity-enhancing patient-generated health data in clinical care and research. Each area will yield one cooperative agreement award, each up to $1 million, with a total available funding of $2 million for fiscal year 2022. Projects can have an initial two-year implementation period, with potential for continued funding in subsequent years based on performance and ONC priorities. Eligible applicants range from public and non-profit organizations to local government units. The application deadline was August 15, 2022. The ONC seeks proposals that engage with underserved communities to address disparities and improve health outcomes, highlighting the importance of utilizing technology to facilitate data sharing and effective healthcare delivery.