Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)
ID: 336548Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/336548

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-22-047.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity through the Alzheimer's Drug-Development Program (U01 Clinical Trial Optional) aimed at advancing the pre-clinical and early-stage clinical development of drugs targeting Alzheimer's disease (AD). This program supports activities such as medicinal chemistry, pharmacokinetics, formulation development, IND-enabling studies, and initial Phase I clinical testing, while excluding applications focused on basic research, generic compounds, or non-pharmacological interventions. With Alzheimer's affecting millions in the U.S., this initiative is crucial for fostering innovative drug development to address this significant healthcare challenge. Eligible applicants can receive funding of up to $1.5 million annually for a maximum of five years, with applications due by November 5, 2024. For further inquiries, interested parties can contact the NIH OER Webmaster at OERWebmaster03@od.nih.gov or visit the additional information link at http://grants.nih.gov/grants/guide/pa-files/PAR-22-047.html.

    Point(s) of Contact
    OERWebmaster03@od.nih.gov
    Files
    Title
    Posted
    PAR-22-047-Full-Announcement.html
    PAR-22-047.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), has reissued the Alzheimer's Drug-Development Program (U01 Clinical Trial Optional). This funding opportunity focuses on advancing pre-clinical and early-stage clinical development of drugs targeting Alzheimer's disease (AD), which currently affects millions in the U.S. Funding supports activities such as medicinal chemistry, pharmacokinetics, formulation development, IND-enabling studies, and initial Phase I clinical testing. Applications that delve into basic research, generic compounds, or non-pharmacological interventions will not qualify. Key dates for submissions span from January 2022 to November 2024, with an application budget capped at $1.5 million annually for up to five years. The program encourages collaboration and requires a detailed project plan including milestones for tracking progress. Eligible applicants range from higher education institutions to non-profit organizations and small businesses. Compliance with quality standards is imperative, with a focus on generating drug candidates suitable for FDA approval. This announcement underscores NIH’s commitment to addressing the growing healthcare challenge posed by Alzheimer’s through innovative drug development initiatives.
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