The National Institutes of Health (NIH) is offering a funding opportunity through the National Center for Complementary and Integrative Health (NCCIH) for multi-site feasibility clinical trials focused on mind and body interventions. This initiative invites applications for investigator-initiated trials that aim to gather essential data necessary for the design of future efficacy or effectiveness studies, specifically addressing recruitment feasibility, intervention fidelity, and data collection methods across multiple sites. The funding, with a maximum budget of $350,000 in direct costs over three years, is intended to advance public health knowledge by exploring complementary health strategies for managing conditions such as pain and anxiety. Interested applicants should note that the application deadlines begin on January 20, 2024, and can find more information at the provided link or by contacting NIH Grants Information at grantsinfo@nih.gov.

PAR-24-083-Full-Announcement.html

PAR-24-083.html

The National Institutes of Health (NIH) is offering a funding opportunity through the National Center for Complementary and Integrative Health (NCCIH) for multi-site feasibility clinical trials focused on mind and body interventions. This opportunity aims to support investigator-initiated trials that gather essential data needed to design future efficacy or effectiveness studies. Proposals must address how the trials will assess recruitment feasibility, intervention fidelity, and data collection methods across multiple sites, leveraging existing preliminary data to justify the research. A critical component includes the submission of a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity in research. The application deadlines begin January 20, 2024, with a maximum budget recommendation of $350,000 in direct costs over 3 years. This funding initiative aligns with NCCIH's objectives to explore complementary health strategies for managing conditions like pain and anxiety, thereby advancing public health knowledge through rigorous scientific inquiry.

https://grants.nih.gov/grants/guide/pa-files/PAR-24-083.html

This notice of funding opportunity (NOFO) invites applications for investigator-initiated clinical trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) in NCCIH-designated areas of high research priority. Applications submitted under this NOFO are expected to propose a multisite feasibility clinical trial that will provide new information that is scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will describe the planned future clinical trial and in so doing demonstrate that the proposed (R01) research is scientifically necessary to design or plan the subsequent fully powered, full-scale clinical trial. Under this R01, the data collected should be used to fill gaps in scientific knowledge, including, but not limited to the following: assessing whether the intervention can be delivered with fidelity across sites; demonstrating feasibility of recruitment, accrual, and randomization of participants across sites; demonstrating participant adherence to the intervention, as well as retention of participants throughout the study across sites; refining and assessing the feasibility of protocolized multimodal interventions, and/or demonstrating feasibility of data collection across sites in preparation for a future fully powered, multisite efficacy or effectiveness trial. The need for multisite feasibility trials is expected to be justified by sufficient preliminary data from previous single site feasibility or acceptability trial(s) or the published literature. The data collected should be used to fill gaps in scientific knowledge and be necessary to develop a competitive fully powered multisite clinical trial that has the potential to make a significant impact on public health.

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

NIH Grants Information&lt;br/&gt;grantsinfo@nih.gov

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