Assessing the Feasibility of Incorporating Mechanisms in Multisite Clinical Trials of Mind and Body Interventions on Whole Person Health Restoration (R01 Clinical Trial Required)
ID: 359941Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Small Businesses

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/359941
Timeline
    Description

    The National Institutes of Health (NIH) is preparing to release a Notice of Funding Opportunity (NOFO) aimed at supporting multi-site feasibility studies of mind and body interventions, such as meditation and yoga, to enhance whole person health restoration. The objective of this funding opportunity is to establish foundational work that will inform future large-scale clinical trials, focusing on the effectiveness of these interventions and their impact on emotional well-being. This initiative is particularly significant as it seeks to enhance the generalizability and reproducibility of findings through studies conducted across multiple geographically distinct sites. Interested applicants, particularly multidisciplinary teams with expertise in complementary health and clinical trial design, should prepare for the anticipated NOFO, which will utilize the R01 Clinical Trial Required activity code. For further inquiries, potential applicants can contact Dr. Jennifer N. Baumgartner at jennifer.baumgartner@nih.gov or by phone at 301-402-4084. The estimated synopsis post date is December 5, 2025, with a closing date expected on February 5, 2026, and project start date anticipated for July 1, 2026.

    Point(s) of Contact
    Jennifer N. Baumgartner, Ph.D. National Center for Complementary and Integrative Health (NCCIH)
    (301) 402-4084
    jennifer.baumgartner@nih.gov
    Files
    No associated files provided.
    Similar Opportunities
    NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Center for Complementary and Integrative Health (NCCIH), has announced a funding opportunity for multi-site feasibility clinical trials focused on mind and body interventions under the R01 grant mechanism. This initiative aims to support studies that gather essential data necessary for planning larger efficacy trials, with specific objectives including assessing recruitment feasibility, intervention fidelity, and participant adherence across multiple sites. The funding is crucial for advancing research in complementary and integrative health, addressing public health challenges, and fostering innovative healthcare approaches. Eligible applicants can request up to $350,000 in direct costs per year, with applications due by November 17, 2026. For further details, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-25-267.html.
    Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms (R61/R33 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms" (R61/R33 Clinical Trial Required). This grant aims to support research on the effects of mind and body interventions, such as mindfulness meditation and yoga, on emotional well-being (EWB) and whole person health (WPH), with a focus on establishing mechanistic insights through rigorous clinical trials. The funding opportunity is particularly significant as it seeks to address the health needs of the American population, with a total commitment of $2 million for FY 2026 to fund three awards, each with a maximum budget of $475,000 per year for up to five years. Interested applicants must submit their proposals by June 7, 2028, and can direct inquiries to grantsinfo@nih.gov for further information.
    NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for multi-site feasibility clinical trials of mind and body interventions through the National Center for Complementary and Integrative Health (NCCIH). This R01 research grant invites applications focused on investigating complementary health approaches that utilize physical or psychological therapies, with an emphasis on demonstrating prior feasibility data to support the multi-site approach. The initiative aims to enhance understanding of integrative health interventions, particularly their efficacy and impact on diverse populations and health disparities. Interested applicants can apply for a maximum project budget of $350,000 annually over a period not exceeding three years, with a submission deadline of January 20, 2024. For further inquiries, applicants may contact NIH Grants Information at grantsinfo@nih.gov.
    Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a grant opportunity titled "Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms." This initiative aims to fund research that investigates how various mind and body interventions, such as mindfulness meditation, yoga, and acupuncture, can enhance whole person health through mechanisms of emotional well-being. The program emphasizes the importance of understanding the biological mechanisms behind these interventions and their potential to improve health outcomes, addressing significant gaps in current research. The estimated total funding for this program is $2 million, with three awards expected to be granted. Interested applicants, particularly small businesses, can reach out to Erin Burke Quinlan, Ph.D., at erin.quinlan@nih.gov or by phone at 301-480-9483 for further information. The application process is set to open on October 14, 2025, with a closing date of December 15, 2025, and anticipated award announcements by July 1, 2026.
    Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Center for Complementary and Integrative Health (NCCIH), is offering a funding opportunity for feasibility clinical trials focused on mind and body interventions addressing high-priority research topics. The objective is to support R34 planning grants that gather essential data necessary for the design and planning of future full-scale efficacy studies, specifically examining aspects such as intervention acceptability, recruitment strategies, and data collection procedures. This initiative is crucial for advancing research in nonpharmacological approaches to symptom management, particularly relevant in the context of increasing healthcare demands. Interested applicants can apply for grants of up to $450,000 over three years, with a submission deadline of November 13, 2026. For further inquiries, applicants may contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-24-084.html.
    Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Center for Complementary and Integrative Health (NCCIH), is inviting applications for the R34 Planning Grant aimed at conducting feasibility clinical trials of mind and body interventions for high-priority research topics. The primary objective of this funding opportunity is to gather essential data necessary for planning future full-scale clinical efficacy or effectiveness studies, with a strong emphasis on addressing gaps in existing knowledge and enhancing public health outcomes, particularly for underserved populations. Eligible applicants include a diverse range of organizations such as higher education institutions, nonprofits, and community-based organizations, with a funding limit of $450,000 over a maximum project period of three years. Interested parties should submit their applications by November 17, 2026, and are encouraged to contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative UG3/UH3 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Center for Complementary and Integrative Health (NCCIH), is offering a funding opportunity for the establishment of a Clinical Coordinating Center (CCC) to support multi-site investigator-initiated clinical trials focused on mind and body interventions. Applicants are required to develop comprehensive plans that include project management, participant recruitment, and data analysis, while collaborating with a corresponding Data Coordinating Center (DCC) to ensure the trials are scientifically robust and aligned with NCCIH's research priorities. This initiative aims to explore the efficacy and effectiveness of complementary health approaches, emphasizing the inclusion of diverse populations and the necessity for a detailed plan to enhance diversity in research teams and subjects. Interested applicants must submit their proposals by January 20, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. For more details, please refer to the full announcement available at https://grants.nih.gov/grants/guide/pa-files/PAR-24-275.html.
    NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a Notice of Funding Opportunity (NOFO) titled "NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)" aimed at supporting mid-phase clinical trials of natural products, including botanicals, dietary supplements, and probiotics, that demonstrate promising preliminary evidence for health benefits. Applicants are required to provide sufficient preliminary data, adhere to FDA regulations, and develop a Plan for Enhancing Diverse Perspectives (PEDP) to foster inclusivity in research, with a focus on determining optimal dosing and patient responsiveness before advancing to larger efficacy trials. This funding opportunity is critical for addressing knowledge gaps in complementary health approaches, particularly in symptom management and health disparities. The estimated total program funding is $350,000, with applications due by November 13, 2026, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the funding opportunity titled "Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth." This initiative encourages the submission of proposals for fully remotely conducted clinical trials aimed at assessing the efficacy of complementary and integrative health interventions, particularly in areas designated as high research priorities by the National Center for Complementary and Integrative Health (NCCIH). The trials must involve no in-person contact between research staff and participants, utilizing mobile health technologies, and applicants are required to provide preliminary data demonstrating the feasibility and safety of their proposed approaches, along with a Plan for Enhancing Diverse Perspectives (PEDP) that will be evaluated during the review process. The application period opens on January 20, 2024, with a submission deadline of February 20, 2026. Interested applicants can find more information and guidance at the NIH website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for investigator-initiated clinical trials focused on complementary and integrative health interventions delivered remotely or via mobile health (mHealth) technologies. Applicants are required to design fully powered clinical trials that do not involve in-person contact between research staff and participants, providing preliminary data on the feasibility, safety, and potential clinical benefits of their proposed interventions. This initiative aligns with the NIH's commitment to addressing public health challenges and expanding access to integrative health approaches, particularly in areas of high research priority identified by the National Center for Complementary and Integrative Health (NCCIH). Interested applicants should note that the submission period opens on January 20, 2025, and must include a Plan for Enhancing Diverse Perspectives (PEDP) as part of their application; for further inquiries, they can contact NIH Grants Information at grantsinfo@nih.gov.