Assessing the Feasibility of Incorporating Mechanisms in Multisite Clinical Trials of Mind and Body Interventions on Whole Person Health Restoration (R01 Clinical Trial Required)

The National Institutes of Health (NIH) is preparing to release a Notice of Funding Opportunity (NOFO) aimed at supporting multi-site feasibility studies of mind and body interventions, such as meditation and yoga, to enhance whole person health restoration. The objective of this funding opportunity is to establish foundational work that will inform future large-scale clinical trials, focusing on the effectiveness of these interventions and their impact on emotional well-being. This initiative is particularly significant as it seeks to enhance the generalizability and reproducibility of findings through studies conducted across multiple geographically distinct sites. Interested applicants, particularly multidisciplinary teams with expertise in complementary health and clinical trial design, should prepare for the anticipated NOFO, which will utilize the R01 Clinical Trial Required activity code. For further inquiries, potential applicants can contact Dr. Jennifer N. Baumgartner at jennifer.baumgartner@nih.gov or by phone at 301-402-4084. The estimated synopsis post date is December 5, 2025, with a closing date expected on February 5, 2026, and project start date anticipated for July 1, 2026.