The National Institutes of Health (NIH) is offering a funding opportunity titled "Building Sustainable Software Tools for Open Science" under the R03 Clinical Trial Not Allowed program. This initiative aims to enhance the sustainability and impact of research software tools by promoting best practices in software development and fostering collaboration between researchers and software engineers, ultimately supporting the advancement of open science practices. The program is particularly important for developing robust and scalable software that ensures research is reproducible, interoperable, and easily disseminated, aligning with NIH's Strategic Plan for Data Science. A total funding commitment of up to $6 million is expected to support 20-24 awards, with each award having a maximum budget of $300,000 over two years. Applications are due by December 4, 2024, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.