The Department of Health and Human Services, specifically the Food and Drug Administration (FDA), is seeking information on literature search and summarization tools to enhance drug safety research. The FDA aims to identify commercial tools that utilize artificial intelligence, particularly natural language processing (NLP), to assist in the classification, summarization, and extraction of relevant medical literature, addressing challenges in evaluating adverse drug reactions. This Request for Information (RFI) is part of a market research initiative and does not constitute a solicitation for contracts; interested parties are encouraged to submit their responses by the specified deadline to Ian Weiss at ian.weiss@fda.hhs.gov, with a focus on the tool's capabilities, interoperability, and validation methods.