The Department of Health and Human Services, through the National Institutes of Health (NIH) and specifically the National Institute of Allergy and Infectious Diseases (NIAID), is seeking qualified small business sources to provide operational, scientific, and administrative support services at the Integrated Research Facility (IRF-Frederick) located at Fort Detrick, Maryland. The primary objective of this Sources Sought Notice is to enhance research capabilities focused on infectious diseases and biodefense, particularly in conducting high-containment studies and evaluating medical countermeasures. The anticipated contract will span one base year with six additional one-year options, emphasizing the need for continuous operation and emergency preparedness in a biosafety level 4 environment. Interested parties must submit their capability statements by April 11, 2025, detailing relevant experience and operational capacity, and can contact Matt Lear at matt.lear@nih.gov or Rosemary Gomes at Rosemary.Gomes@nih.gov for further information.