A--Repository of Mouse Models for Down Syndrome
ID: 75N94025R00007Type: Presolicitation
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTES OF HEALTH NICHDBETHESDA, MD, 20817, USA

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714)

PSC

HEALTH R&D SERVICES; HEALTH CARE SERVICES; APPLIED RESEARCH (AN12)
Timeline
  1. 1
    Posted Apr 3, 2025, 12:00 AM UTC
  2. 2
    Updated Apr 3, 2025, 12:00 AM UTC
  3. 3
    Due Apr 18, 2025, 7:00 PM UTC
Description

The Department of Health and Human Services, through the National Institutes of Health (NIH) and specifically the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), is announcing its intent to negotiate a sole-source contract with Jackson Laboratory for the establishment and maintenance of a Repository of Mouse Models for Down Syndrome. This initiative aims to produce, acquire, maintain, and distribute genetically characterized mouse models, particularly focusing on the Ts65Dn strain, to support cytogenetic research related to Down syndrome. The contractor will also be responsible for essential tasks such as cryopreservation, pathogen testing, and phenotypic characterization, with ongoing consultations with a Scientific Advisory Board to align with the research community's needs. Interested parties are encouraged to submit capability statements by the specified deadline, as this contract is anticipated for one year with options for four additional periods, and is not currently open for competitive proposals. For further inquiries, contact Dana L. Harris at harrisd@mail.nih.gov or +1 301 443 7798.

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Title
Posted
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is announcing its intent to negotiate a sole-source contract with Jackson Laboratory for the establishment and maintenance of a Repository of Mouse Models for Down Syndrome. This initiative aims to supply the Down syndrome research community with genetically characterized mouse models, specifically maintaining and breeding the established Ts65Dn strain and potentially new strains as they become available. The contractor will also be responsible for cryopreservation procedures, pathogen testing, and phenotypic characterization of the mice. Regular consultations will be held with a Scientific Advisory Board to ensure meeting the community's research needs. The contract is anticipated for one year with the option for four additional periods and is not currently a request for competitive proposals. Interested parties are invited to submit capability statements by a specified deadline. The focus of this notice is to communicate the government's intent to source specialized mouse model services with a unique capability offered solely by Jackson Laboratory, reflecting the needs of the Down syndrome research field.
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