Office-Wide Innovative Solutions Opening
ID: ARPA-H-SOL-24-104Type: Presolicitation
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)Bethesda, MD, 208920004, USA

PSC

HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT (AN13)

Original Source

https://sam.gov/opp/0f71794fda5b47b68ee28139c2468fdb/view
Timeline
    Description

    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is soliciting proposals for the Innovative Solutions Opening (ISO) aimed at advancing healthcare technologies. This initiative seeks innovative, disease-agnostic research projects that can significantly improve health outcomes, focusing on areas such as maternal and fetal health, genetic therapies, and novel diagnostic tools. The solicitation emphasizes the development of transformative solutions rather than incremental research, with submissions required to follow a two-step process: an initial solution summary followed by a full proposal based on feedback received. Interested parties must submit their solution summaries by March 3, 2029, via the designated ARPA-H portal, and are encouraged to review the detailed submission guidelines outlined in the provided documentation.

    Point(s) of Contact
    SEE DESCRIPTION SECTION
    do_NOT_use_THIS_email_ADDRESS@arpa-h.gov
    Files
    Title
    Posted
    A07_HSF_ISO_Amend_1.pdf
    The Advanced Research Projects Agency for Health (ARPA-H) has announced the Innovative Solutions Opening (ISO) under solicitation number ARPA-H-SOL-24-104, inviting proposals for groundbreaking healthcare technologies. This solicitation aims to support innovative, disease-agnostic research projects that can significantly enhance health outcomes. Key interest areas include breakthrough technologies for maternal and fetal health, genetic and cellular therapies, and novel diagnostic tools. Eligible participants include universities, non-profits, and small businesses, with a deadline for submission set until March 3, 2029. Proposers must initially submit a solution summary for feedback before proceeding with full proposals, which will be evaluated based on scientific merit, relevance to ARPA-H’s mission, and proposer capabilities. The solicitation emphasizes transformative, high-impact solutions over incremental research and excludes proposals for traditional policy changes or infrastructure projects. Awards will primarily include Other Transactions and Cooperative Agreements, allowing for flexibility in negotiation without the constraints of Federal Acquisition Regulation. The process encourages innovative approaches that incorporate open standards and interoperability in healthcare technology.
    Appendix A - Solutions Summary Template.docx
    The ARPA-H solicitation document outlines the requirements for submitting solution summaries in response to government Requests for Proposals (RFPs). It emphasizes the need for clarity and innovation in proposed technology concepts that address high-priority interest areas. Key sections include a Concept Summary where submitters detail their solutions and the problems they address, and Innovation and Impact, where the potential disruptiveness and superiority of the proposal over existing technologies should be demonstrated with measurable metrics. Additionally, the document specifies the Proposed Work section, where deliverables, milestones, and technical approaches must be clearly outlined alongside an analysis of technical challenges and risks. Team Organization and Capabilities highlight the roles of project members, supported by a Basis of Estimate (BOE) detailing financial requirements, work breakdown, and project costs. Submissions are restricted to six pages and must be formatted according to specified guidelines, ensuring readability and organization. This document serves to enhance the clarity and effectiveness of proposals within the context of federal funding opportunities, focusing on innovative solutions in healthcare and related fields.
    Attachments - Bundle of Attachments.zip
    Bundle_of_Attachments-Amend_1.zip
    HSF Open Office Innovative Solutions Opening.pdf
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