The Department of Health and Human Services, specifically the Centers for Disease Control and Prevention (CDC), intends to award a sole source contract to Metro Health for access to the Epic Cosmos electronic health record (EHR) dataset. This dataset encompasses EHR information from over 240 million patients across all 50 states, providing real-time updates and critical features such as automatic vaccine data downloads and maternal-infant outcome assessments. The unique nature of the Cosmos database, which cannot be accessed through commercial means, underscores its significance for evaluating real-world effectiveness, particularly concerning rare health outcomes. Interested parties may express their interest and capability to respond to this requirement by contacting Cole Mullis at ttu3@cdc.gov within 15 days of this notice, as the government will consider all responses before deciding on the competitive procurement process.