The Department of Health and Human Services, specifically the Agency for Healthcare Research and Quality (AHRQ), is seeking qualified small businesses to participate in the Evidence-based Practice Center (EPC) Program through a Small Business Sources Sought notice. The primary objective is to develop systematic reviews that adhere to established methodologies for evaluating healthcare outcomes, quality, and safety, with a focus on areas such as metastatic prostate cancer and cognitive behavioral therapy for depression. These evidence reviews are crucial for informing clinical guidelines and improving healthcare delivery, and the work will be performed remotely under various task orders. Interested small businesses must submit a tailored capability statement by 12:00 PM on January 2, 2025, to Alyssa Tornatore at Alyssa.Tornatore@ahrq.hhs.gov, detailing their qualifications and relevant experience.