The National Institute of Standards and Technology (NIST) is seeking information from potential vendors for a hardware and software upgrade for the IMS 1280 mass spectrometer. The procurement aims to enhance the instrument control software and computer systems, including necessary cables and OEM software, along with a software manual. This upgrade is crucial for maintaining the operational efficiency of the analytical laboratory instrument, which plays a significant role in various scientific applications. Interested parties are encouraged to submit their capabilities and relevant information to Don Graham at deg@nist.gov by the specified response date, as NIST anticipates issuing a Request for Quotation in early FY2025, with contract awards expected by the third quarter of FY2025.