Proposers’ Day Announcement for ARPA-H Computational ADME Tox AnaLYsis for Safer Therapeutics (CATALYST)
ID: ARPA-H-SN-24-114Type: Special Notice
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)Bethesda, MD, 208920004, USA

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714)

Original Source

https://sam.gov/opp/2eecb002d9d54533aae6cb7867af28d6/view
Timeline
    Description

    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is announcing a Proposers’ Day for the Computational ADME Tox AnaLYsis for Safer Therapeutics (CATALYST) program, scheduled for October 29, 2024, in Cincinnati, OH. This initiative aims to engage the scientific community in developing AI/ML-enabled in silico human physiology modeling platforms to reduce reliance on animal studies in drug safety assessments, ultimately enhancing drug efficacy predictions and expediting the drug approval process. The CATALYST program is structured in two phases, focusing on technology development and regulatory demonstration, and participation in the Proposers' Day is encouraged for those interested in collaboration, although it is not mandatory for proposal submissions. Interested parties should register for the event and can reach out to CATALYST@arpa-h.gov for further information.

    Point(s) of Contact
    CATALYST@arpa-h.gov
    Files
    Title
    Posted
    CATALYST Special Notice ARPA-H-SN-24-114.pdf
    The Advanced Research Projects Agency for Health (ARPA-H) is hosting a Proposers’ Day for the Computational ADME Tox AnaLYsis for Safer Therapeutics (CATALYST) program on October 29, 2024, in Cincinnati, OH. This event aims to engage the scientific community regarding this innovative program designed to develop AI/ML-enabled in silico human physiology modeling platforms to replace animal studies in drug safety assessments. The Proposers' Day will include presentations, three-minute lightning talks, and private meetings for attendees to discuss collaboration opportunities and program details. Participation is encouraged but not mandatory for proposal submissions. The CATALYST program seeks to create effective in silico models for drug development, minimizing reliance on animal testing and improving prediction accuracy for drug efficacy, ultimately expediting the drug approval process and enhancing patient safety. The program is divided into two phases, focusing first on technology development and qualification, followed by regulatory demonstration and methodology adoption. Registration is required for participation, with capacity limits for in-person attendance and specific deliverables requested from attendees. The event aligns with ARPA-H’s goal to foster innovation in healthcare through collaborations aimed at achieving equitable healthcare outcomes for all Americans.
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