CANCELLED_PROactive Solutions for Prolonging Resilience (PROSPR) Proposers' Day
ID: ARPA-H-SN-25-125Type: Special Notice
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)Bethesda, MD, 208920004, USA

NAICS

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) (541715)

PSC

HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT (AN13)
Timeline
    Description

    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), has announced the cancellation of the Proposers' Day event for the PROactive Solutions for Prolonging Resilience (PROSPR) program, originally scheduled for January 24, 2025. This program aims to extend individuals' healthspan by 20 years and prevent age-related diseases, focusing on developing an Intrinsic Capacity (IC) score, repurposing FDA-approved drugs, and advancing innovative healthspan interventions. Although the Proposers' Day has been cancelled, the draft Innovative Solutions Opening (ISO) is anticipated in December 2024, with a final ISO expected in January 2025, and interested parties are encouraged to register and submit teaming profiles by January 21, 2025. For further inquiries, contact the PROSPR Team at PROSPR@arpa-h.gov.

    Point(s) of Contact
    The PROSPR Team
    PROSPR@arpa-h.gov
    Files
    Title
    Posted
    The Advanced Research Projects Agency for Health (ARPA-H) announces a Proposers’ Day event on January 24, 2025, regarding the PROactive Solutions for Prolonging Resilience (PROSPR) Program. This program aims to develop interventions that extend healthspan by 20 years by addressing age-related health decline and accelerating the research and development of therapeutics. The day will promote engagement within the research community, clarify program objectives, and encourage collaboration among potential project performers. The PROSPR program focuses on three main technical areas: developing an intrinsic capacity (IC) score for tracking health outcomes, repurposing FDA-approved drugs for healthspan extension, and advancing innovative preclinical interventions. The event will be hybrid, held in-person in Dallas, Texas, and virtually via Zoom, with a limited number of presentations and networking opportunities. Registration is required by January 21, 2025, and interested parties can submit "teaming profiles" to connect with potential collaborators. This event is informational and voluntary, with no obligation to submit proposals. The highlighting aspect is the removal of lengthy clinical trials, paving the way for efficient healthspan therapeutics development, and ultimately transforming geriatric medicine into a proactive model emphasizing preventative care.
    The Advanced Research Projects Agency for Health (ARPA-H) is hosting a virtual Proposers’ Day event for the PROactive Solutions for Prolonging Resilience (PROSPR) program on January 24, 2025. This program seeks to extend Americans' healthspan by 20 years by addressing the underlying causes of health deterioration related to aging, aiming to prevent multiple age-related diseases simultaneously. Proposals focusing on three technical areas are encouraged: the development of a composite intrinsic capacity score for health prediction, repurposing of FDA-approved drugs for healthspan extension, and innovation in preclinical interventions to enhance healthspan. The Proposers’ Day will introduce attendees to program goals, clarify logistics, and promote collaboration among potential performers. Registration is required by January 21, 2025, and is open for both virtual and in-person attendance in Dallas, Texas. The event will feature presentations and opportunities for networking, including lightning talks for participants to discuss their capabilities and desired partnerships. Overall, this initiative underscores ARPA-H's commitment to advancing healthcare solutions focusing on proactive health management and preventive care for aging populations while transforming geriatric medicine into a more personalized model.
    The Advanced Research Projects Agency for Health (ARPA-H) has issued a Special Notice for the PROactive Solutions for Prolonging Resilience (PROSPR) program, aimed at extending individuals' healthspan by 20 years and preventing age-related diseases. The Proposers’ Day event scheduled for January 24, 2025, has been cancelled, and the draft Innovative Solutions Opening (ISO) is expected in December 2024, with a final ISO in January 2025. The program emphasizes developing an Intrinsic Capacity (IC) score, repurposing FDA-approved drugs, and advancing innovative healthspan interventions. Attendees should register by January 21, 2025, and submit teaming profiles outlining their technical competencies and collaboration interests. The event will include presentations and opportunities for "lightning talks" to foster collaboration among potential performers. It is important to note that attendance is voluntary and does not obligate participants to submit proposals. The notice serves solely for informational purposes and does not solicit proposals at this time.
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