The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is hosting a Proposers’ Day on January 24, 2025, to discuss the PROactive Solutions for Prolonging Resilience (PROSPR) Program. This initiative aims to develop innovative interventions that extend healthspan by addressing age-related health decline and accelerating the research and development of therapeutics, focusing on three key areas: creating an intrinsic capacity score for health outcomes, repurposing FDA-approved drugs, and advancing preclinical interventions. The event will be held in a hybrid format in Dallas, Texas, and virtually, promoting engagement and collaboration within the research community, with registration required by January 21, 2025. Interested parties can connect with potential collaborators by submitting "teaming profiles" and can reach out to the PROSPR Email Box at PROSPR@arpa-h.gov for further information.