The Department of Defense (DoD) is seeking innovative technologies and approaches to eliminate cold chain requirements for the storage and transportation of medical countermeasures (MCM). The objective is to enhance the efficiency and expeditionary capabilities of MCM administration by minimizing logistical constraints, focusing on the assessment of existing DoD-developed MCMs alongside thermostabilizing technologies, alternative formulations, and novel administration routes. This initiative is critical for improving the stability and efficacy of MCMs, ultimately benefiting both military and civilian healthcare systems. The solicitation is set to open on January 29, 2025, with applications due by February 26, 2025. Interested parties can find more information and submit proposals through the DoD SBIR website at https://www.dodsbirsttr.mil/topics-app/.