The National Institutes of Health (NIH) and The Centers for Disease Control and Prevention (CDC) are seeking proposals for the development of next-generation devices and materials-based platforms for the administration of HIV1 broadly neutralizing antibodies. The goal is to improve the delivery of these antibodies for HIV prevention or other indications. The research aims to enhance potency, increase tissue levels, extend half-life, and target multiple sites of vulnerability on the HIV Envelope glycoprotein. The project duration for Phase I is up to 1 year with a budget of $300,000, while Phase II has a duration of up to 3 years with a budget of $2 million. The solicitation is closed, and 1-3 awards are anticipated. The research may involve the development of dermal patches, controlled-release hydrogels, nanoparticle carriers, vaginal rings, implantable devices, and nucleic acid delivery systems. The expected impacts include increased end-user acceptability, improved adherence, reduced administration-associated cost and time, and improved efficacy by maintaining sustained antibody titers. For more information, refer to the solicitation notice on grants.gov.