The National Institutes of Health (NIH) is announcing an upcoming funding opportunity for the establishment of an ancient DNA for Modern Genomics (aDMG) Data Generation and Resource Center. This initiative aims to create an ethical resource of ancient and historical human DNA data to enhance research on contemporary human traits and biology, with a focus on producing high-quality whole-genome sequence data from approved ancient DNA sources. The program is significant for advancing studies in population genomics and human evolution, encouraging collaborations among experts in DNA sequencing, computational genomics, and related fields. The estimated total program funding is $2,750,000, with one award expected, and interested applicants should prepare for the application process, which will open following the publication of the Notice of Funding Opportunity (NOFO) in December 2025, with a closing date in March 2026. For further inquiries, potential applicants can contact Jennifer Troyer at jennifer.troyer@nih.gov or by phone at 301-312-3276.