The Centers for Disease Control and Prevention (CDC) is offering a funding opportunity aimed at strengthening the technical capacity of the Ministry of Health in the Kingdom of Eswatini to effectively respond to HIV, TB, and related public health threats under the PEPFAR initiative. The primary objectives include enhancing programmatic leadership, health workforce capacity, and organizational oversight in HIV/TB services, with a focus on strategic planning, policy development, and the implementation of innovative interventions. This initiative is critical for sustaining and improving health services in Eswatini, ultimately aiming to end HIV as a public health threat by 2030. Interested applicants can submit their proposals by March 5, 2025, with an estimated funding amount of $3.5 million for the first year, and should direct inquiries to Emily Dale at pepfarfoas@cdc.gov.