The Department of Health and Human Services, through the National Institutes of Health (NIH), has announced a funding opportunity to investigate the long-term effects of disasters on healthcare systems for populations experiencing health disparities in the U.S. and its territories. This initiative, designated as PAR-24-109, invites collaborative research to better understand how disasters—both natural and human-made—impact vulnerable populations and their healthcare access, delivery, and infrastructure over time. Key research objectives include assessing direct long-term effects on healthcare systems, evaluating interventions, and enhancing resilience strategies. Applications are encouraged from diverse organizations, including educational institutions and nonprofits, with a maximum funding period of five years. The application process is detailed, requiring adherence to several specific guidelines and submission protocols. The initiative aims to derive lessons that could inform healthcare policy and improve service delivery for disadvantaged communities affected by disasters. Key deadlines for submission range from May 2024 to May 2027, with specific review cycle dates set. Overall, this funding opportunity emphasizes the need for research that addresses the intersection of disaster response and health equity, acknowledging the unique challenges faced by marginalized groups during and post-disaster events.