The National Institutes of Health (NIH) has announced a funding opportunity (R01 - Clinical Trial Not Allowed) aimed at supporting research to engineer improved stem cell-derived islet cells for replacement therapies, particularly for Type 1 Diabetes. This grant seeks to enhance the intrinsic characteristics of stem cell-derived islet cell products to improve graft viability and function, encouraging studies on engineering approaches and preclinical testing. The initiative is part of the Special Diabetes Program, which funds innovative research on the prevention, treatment, and cure of Type 1 Diabetes and its complications. Interested applicants can apply for a total estimated funding of $3 million, with an award ceiling of $500,000 per project, and must submit their applications by March 7, 2026. For further inquiries, contact Albert Hwa at NIDDK_DEM@nih.gov.