Summary: The Mozambique USAID-Maputo is seeking information for a new activity called "Ensuring Social Protection by Empowering and building Resiliency for Adolescents, Nuclear families, Children, and caregivers affected by HIV/AIDS (ESPERANÇA)". This activity aims to support the Government of Mozambique in reaching and sustaining HIV epidemic control in three provinces - Sofala, Manica, and Tete. The activity is expected to be a five-year award with a total value of up to $40 million. The purpose of this request is to assess the interest of potential organizations, gain insights into their capacity, explore innovative approaches to partnering, and collect inputs to improve the proposed Program Description/Scope of Work. Responding to this request does not guarantee any advantage in the subsequent procurement process.